Immunometabolism: IL-37 fights inflammation-induced fatigue

Nature Reviews Rheumatology 13, 258 (2017).
doi:10.1038/nrrheum.2017.28

Author: Sarah Onuora
New research by Giulio Cavalli and colleagues shows that the IL-1 family cytokine IL-37 not only has anti-inflammatory effects, but also induces metabolic reprogramming both in the context of inflammation-induced fatigue and in healthy mice. “We demonstrate a remarkable property of IL-37 to limit the

Source: Nature Reviews Rheumatology - March 2, 2017 Category: Rheumatology Authors: Sarah Onuora Tags: Research Highlight Source Type: research