Skin-derived precursors from human subjects with type-2 diabetes yield dysfunctional vascular smooth muscle cells.
Conclusion: Skin biopsies from older adults yield sufficient SKPs to differentiate VSMCs, which reveal abnormal phenotypes of T2D that survive differentiation and persist even after long-term normoglycemic culture.
Source: Clinical Science - Category: Biomedical Science Authors: Steinbach, S. K., Yau, T. M., Ouzounian, M., Abdel-Qadir, H., Chandy, M., Waddell, T., Husain, M. Tags: PublishAheadOfPrint Source Type: research
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