Meta-analysis supports progesterone for recurrent pregnancy loss

A study inFertility and Sterility has reviewed the evidence for progesterone supplementation in women who experience frequent unexplained miscarriage.Medscape 
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

Related Links:

Publication date: Available online 15 February 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Theodoros D. Theodoridis, Panagiotis Pappas, Grigoris F. GrimbizisAbstractThe prevalence of congenital uterine anomalies (CUA) is reported to be 4,3-6,7% in the general population, 3,4-8% in the infertile population and 12,6-18,2% among those with recurrent miscarriages. They are the result of abnormal formation, differentiation and fusion of the Mu¨llerian or paramesonephric ducts during fetal life.Until now, various classification systems have been proposed for the categorization of Co...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
CONCLUSION: In women with infertility undergoing fertility work-up, tubal flushing with oil-based contrast probably increases clinical pregnancy rates within 6 months and may increase subsequent live birth rates, compared to tubal flushing with water-based contrast and compared to no intervention. Evidence on fertility outcomes beyond 6 months is insufficient. This article is protected by copyright. All rights reserved. PMID: 30740799 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
AbstractStudy objectiveTo compare pregnancy outcomes in PCOS women undergoing transvaginal ovarian injury (TVOI) and laparoscopic ovarian drilling (LOD)Design126 infertile patients with PCOS were included in this prospective cohort studyCanadian task force classification of level of evidenceIIA.SettingUniversity-affiliated fertility center.PatientsSixty-seven infertile patients with the history of failed in vitro maturation underwent follow-up as the TVOI group. Fifty-nine infertile women who underwent LOD acted as controls. All subjects had PCOS with menstrual irregularity and were anovulatory by repetitive serum progeste...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
CONCLUSION: Although limited by heterogeneity, studies of ovarian stimulation in women with unexplained infertility show no difference in clinical outcomes between letrozole and clomiphene citrate. PMID: 30741800 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
The objective of the present systematic review and meta-analysis was to compare surgical and expectant management of endometriomas regarding IVF outcomes. Prospective and retrospective controlled studies were found via the Cochrane Library, Embase, and MEDLINE databases. Thirteen studies (1 randomized controlled trial and 12 observational studies, N = 2878) were pooled, and similar live birth rates were observed in the surgically and expectantly managed groups (odds ratio = 0.83; 95% confidence interval [CI], 0.56–1.22; p = .98). The clinical pregnancy rates (odds ratio = 0.83; 95% CI, 0.66–1.05...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionFour different types of endometrial preparation methods for FET cycles appear to be equally effective in terms of implantation, pregnancy, miscarriage and live birth rates in women with normal menstrual cycles.Clinical Trial Registration Number: NCT02251925.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Conclusionswe suggest that women with infertility may represent a subpopulation of patients with underhanded systemic autoimmune syndromes in which the main symptoms represented are obstetrical complications. We, therefore, recommend evaluating aPLs in all patients undergoing IVF with the aim of recognizing women at a higher risk of miscarriage or pregnancy morbidity.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
By Mallory Michalak, 2018 UNC-IntraHealth Summer FellowJanuary 09, 2019Midwife Tembi Mugore answers four questions about bias, shame, and what it takes to overcome them in health services for young people.At least 8% of maternal deaths worldwideare from unsafe abortions. And almost all abortion-related deaths occur in low- and middle-income countries,mostly in Africa.“But there is a stigma attached to unsafe abortion, and because of that there is a bias against clients,” saysIntraHealth International midwife and public health professional Stembile Mugore. That bias prevents many clients —particularly yo...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Evidence to Action (E2A) Project Family Planning & Reproductive Health Maternal, Newborn, Child Health Education Performance Advocacy Quality of Care Youth Midwives Togo Source Type: news
This study showed that LAH via zona pellucida (ZP) thinning significantly improves clinical outcomes, particularly clinical pregnancy and implantation rates, associated with FET cycles among patients with previous repeated failure.
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
ConclusionsWomen with suspected endometriosis and aberrant endometrial BCL6 expression have worse reproductive outcomes following embryo transfer, including a high miscarriage rate, poor IR, and low LBR and CPR compared to cycles pre-treated with medical and surgical management.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
More News: Endocrinology | Infertility | Miscarriage | Pregnancy | Reproduction Medicine | Study | Women