mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression

Conclusions The presented staining panel could be appropriate and highly recommended for the accurate specification of mTORC1 and C2 activity of tumour tissues. This could help in the selection of mTOR inhibitors and can provide information about prognosis, which may guide decisions about the intensity of therapy.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Tags: Colon cancer Original article Source Type: research