Editorial commentary: “Discovery of a Murine Model of clinical pulmonary arterial hypertension: Mission impossible?” by Dai and Zhao

Pulmonary hypertension (PH) is defined as a mean pulmonary arterial pressure of ≥25mmHg at rest, which is determined by right heart catheterization [1]. The condition is further characterized by a progressive increase of pulmonary vascular resistance leading to right ventricular failure and death [2]. The clinical classification of PH categorizes multiple clinical conditions into five groups according to clinical presentation/etiology, histologic findings, hemodynamic characteristics and treatment strategy.

Source: Trends in Cardiovascular Medicine - January 10, 2017 Category: Cardiology Authors: Gerald J. Maarman Source Type: research