Correlation between serum uric acid levels and residual platelet reactivity in patients undergoing PCI

Uric acid has been demonstrated within atherosclerotic plaque, where it may lead to thrombus formation by increasing platelet adhesiveness and altering the normal platelet reactivity [1,2]. Increased platelet reactivity has been associated with ischemic events in patients with coronary atherosclerosis [3]. In particular, recurrent ischemic events and increased risk of stent thrombosis were reported in patients undergoing percutaneous coronary intervention (PCI) in the presence of high residual platelet reactivity (HPR) despite treatment with dual anti-platelet therapy (DAPT) with aspirin (ASA) and P2Y12 inhibitors (e.g.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Tags: Letter to the Editor Source Type: research