Artificial lung the size of a sugar cube

(Fraunhofer-Gesellschaft) What medications can be used to treat lung cancer, and how effective are they? Until now, drug companies have had to rely on animal testing to find out. But in the future, a new 3-D model lung is set to achieve more precise results and ultimately minimize -- or even completely replace -- animal testing. From June 23-26, researchers will be presenting their new model at the BIO International Convention in San Diego, Calif.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Development of primary lung cancer in donor lung post-lung transplantation is very rare, with few described cases. The safety of stereotactic ablative radiotherapy (SABR) for early-stage lung cancer arising fr...
Source: Radiation Oncology - Category: Cancer & Oncology Authors: Tags: Case report Source Type: research
Authors: Wang X, Cheng L, Xie HJ, Ju RJ, Xiao Y, Fu M, Liu JJ, Li XT Abstract Treatment effect of chemotherapy for aggressive non-small-cell lung cancer (NSCLC) is usually unsatisfactory for non-selective distributions of anticancer drugs, generation of vasculogenic mimicry (VM) channels, high metastasis and recurrence rate. Therefore, we developed a kind of dequalinium (DQA) modified paclitaxel plus honokiol micelles in this study to destroy VM channels and inhibit tumour metastasis. In vitro assays indicated that the targeting paclitaxel micelles with ideal physicochemical characteristics could exhibit not only t...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Internal documents from IBM Watson Health (NYSE:IBM) indicate that the company’s Watson for Oncology product often returns “multiple examples of unsafe and incorrect treatment recommendations,” according to a new report from STAT News. The documents come from slides presented last year by IBM Watson Health’s deputy chief health officer, according to the report, and include feedback from customers that indicated the product is “often inaccurate” and that its recommendations bring to light “serious questions about the process for building content and the underlying technology.&r...
Source: Mass Device - Category: Medical Devices Authors: Tags: Oncology Software / IT IBM Watson Health Source Type: news
Source: Artificial Cells, Blood Substitutes, and Biotechnology - Category: Biotechnology Authors: Source Type: research
It ’s difficult to open a newspaper nowadays without seeing an article about artificial intelligence. These column-inches spark our imaginations with heady visions of possible futures and crease our brows with concern in equal measure. But one thing you cannot escape is that AI is here now and it’s only going to become more pervasive.While fear of an unknown technology is understandable, in many ways it does a disservice to the incredible impact that AI is already having on the world around us. In the healthcare space alone, it is offering ways to fundamentally rethink clinical practice, speeding up diagnosis, ...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
The U.S. Food and Drug Administration (FDA) has cleared artificial intelligence...Read more on AuntMinnie.comRelated Reading: Mirada upgrades radiation treatment software Mirada introduces AI software for radiation oncology Optellum, Mirada present lung cancer study at RSNA 2017 Mirada's deep-learning contours match human-drawn contours Mirada showcases XD:PACS at RSNA 2016
Source: Headlines - Category: Radiology Source Type: news
A 39-year-old non-smoker woman was admitted in the thoracic oncology unit of the Montpellier Academic Hospital in June 2017 for investigation of multiple lung consolidations, fever, and respiratory failure. She was followed-up since infancy for a cystic fibrosis with cystic fibrosis transmembrane conductance regulator (CFTR) mutation ( ΔF508-CFTR). Two years ago, a lung allograft was decided, owing to rapid onset of respiratory function impairment, and she received a bi-pulmonary transplant. According to the donor database, the lung transplant was removed from a 57-year-old woman with a 30 pack-year smoking history.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: In our setting, excluding NMSC, the incidence is 8.8 times greater than estimations for the general population, with a high rate of lung cancer, so we should implement preventive and diagnostic strategies. PMID: 30017062 [PubMed - as supplied by publisher]
Source: Cirugia eEspanola - Category: Surgery Authors: Tags: Cir Esp Source Type: research
CONCLUSIONS: To date, data on OS, quality of life, PFS, response rate, or short- and long-term AEs are available from small uncontrolled trials only. The three trials included heavily pretreated participants, which had previously undergone regimens of BV or ASCT. For these participants, median OS was not reached after follow-up times of at least 16 months (more than 50% of participants with a limited life expectancy were alive at this timepoint). Only one cohort out of three only reported quality of life, with limited follow-up data so that meaningful conclusions were not possible. Serious adverse events occurred rarely. C...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Publication date: May 2018Source: Journal of Applied Biomedicine, Volume 16, Issue 2Author(s): Reema Shyamsunder Shukla, Yogender AggarwalAbstractLung cancer is uncontrolled growth of cells that occurs due to exposure to smoke, radiation and chemicals, which causes chronic stress and associated with impaired autonomic nervous system. Nonlinear heart rate variability (HRV) analysis has been suggested to uncover the performance status of lung cancer subjects and distinguish them from healthy controls. The present work obtained tachogram from recorded electrocardiogram of 104 lung cancer subjects and 30 healthy controls to ex...
Source: Journal of Applied Biomedicine - Category: Biotechnology Source Type: research
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