Physical Activity and Adiposity-related Inflammation: The MESA

This study examined whether associations of physical activity and obesity-related inflammatory markers were independent of central adiposity. Methods: Between 2002 and 2005, 1970 participants from the Multi-Ethnic Study of Atherosclerosis completed detailed health history and physical activity questionnaires, underwent physical measurements including computed tomography to quantify abdominal visceral and subcutaneous fat, and measurements of adiponectin, leptin, interleukin-6, tumor necrosis factor-alpha, and resistin. Statistical analyses included analysis of covariance and multivariable-adjusted regression. Results: The mean (range) age of participants was 64.7 (55–84) yr and 50% were women. After adjustment for age and sex, and compared with the lowest quartile, inflammatory markers in the highest quartile of moderate-to-vigorous physical activity were 16% higher for adiponectin and 30%, 26%, and 9% lower for leptin, interleukin-6, and resistin, respectively (P
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: Epidemiology Source Type: research