Subclinical inflammation associated with prolonged TIMP-1 upregulation and arterial stiffness after gestational diabetes mellitus: a hospital-based cohort study

Gestational diabetes mellitus (GDM) has significant implications for the future health of the mother. Some clinical studies have suggested subclinical inflammation and vascular dysfunction after GDM. We aimed ...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Source Type: research

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ConclusionsBlood glucose fluctuation is an independent risk factor associated with CIMT in T2DM patients, in addition to conventional risk factors, such as smoking, high UA level and 2  h C-peptide. Therefore, more attention should be given to the change of CIMT and the complications.
Source: European Journal of Medical Research - Category: Research Source Type: research
Abstract To fight against diabetes mellitus, from which more than 400 million people suffer in the world, the patients have to puncture their fingers 4-5 times a day for the blood glucose level checks when using a glucometer, causing invasive pain and the risk of infection. Therefore, non-invasive method has been urged for blood glucose monitoring, among which the mid-infrared spectroscopy (Mid-IR) response of interstitial fluid was found to be promising. However, despite the prolonged effort, the accuracy still falls below the FDA's requirement. To break this barrier which lasted for almost three decades, we disc...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
ConclusionsWe describe a novel method to calculate the prevalence of pediatric DM in a primary care population. This case definition will improve pediatric DM surveillance, and enhance service planning and the development of strategies to support prevention and management.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Publication date: Available online 18 February 2019Source: Canadian Journal of DiabetesAuthor(s): Amélie Ardilouze, Patricia Bouchard, Marie-France Hivert, Catherine Simard, Catherine Allard, Marie-Pierre Garant, Julie Ménard, Annie Ouellet, Ghislaine Houde, Marie-Hélène Pesant, Jean-Patrice Baillargeon, Jean-Luc ArdilouzeAbstractObjectivesTo compare: 1) 75g-oral glucose tolerance test (OGTT) and self-monitoring of blood glucose (SMBG) in identifying gestational diabetes mellitus (GDM) and other hyperglycemic statuses in pregnant women, 2) pregnancy outcomes according to glycemic status, and 3) ...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Peddanna Kotha, Saritha Marella, Rajasekhar Allagadda, Kameswara Rao Badri, Appa Rao ChippadaAbstractAnisomeles malabarica (AM) is an aromatic plant traditionally used for the treatment of diabetes mellitus in India. Following bioassay guided fractionation, we recently identified an active fraction of AM (AMAF, with potential mix of active principles) that showed significant antihyperglycemic and antihyperlipidemic activities. In addition, AMAF treatment improved insulin levels. However, the biochemical mechanism/s through which AMAF...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Introduction: Gestational diabetes mellitus is significantly associated with adverse maternal and fetal outcomes, especially increased number of cesarean deliveries, newborns large for gestational age and macrosomia. Consequently, early diagnosis plays a crucial role in the management of this which helps a pregnant woman and the physician to develop a plan to help manage any possible complications.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 16 – Obstetrics: High risk pregnancy Source Type: research
Introduction: Gestational diabetes mellitus (GDM) impacts approximately 10 –15% of pregnancies worldwide. Currently the recommendation is that pregnancies affected with GDM requiring medication should be delivered by their due date. There is a paucity of evidence to support that induction of labour would be beneficial. Evidence derived from other studies support that ind uctions do not increase the caesarean section rate. The aim of this study is to assess whether induction of labour for GDM increases the caesarean section (LSCS) rate.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 27 – Obstetrics: Induction of labour, delivery and breech Source Type: research
Introduction: Maternal body composition undergoes deep adaptative changes during pregnancy, especially in many pathological conditions, such as gestational diabetes mellitus (GDM).
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 11 – Obstetrics: Obesity and diabetes Source Type: research
Introduction: Retrospective analysis report that women carrying a male fetus are at increased risk of gestational diabetes mellitus (GDM); however, data from well-designed prospective studies? are lacking.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 11 – Obstetrics: Obesity and diabetes Source Type: research
Introduction: Preeclampsia is a hypertensive disorder combined with proteinuria and occurs only during pregnancy. The condition is potentially dangerous for the mother and the foetus, and is one of the most common reasons for maternal and foetal mortality and morbidity globally. The aetiology is still unknown, but many risk factors are identified. Risk of preeclampsia is higher among nulliparous women compared with parous women. Advanced maternal age, obesity, diabetes mellitus and pre-pregnancy hypertension increase the risk of preeclampsia.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Session 10 – Obstetrics: Hypertension Source Type: research
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