A 20-Month-Old Girl with Fever, Seizures, Hemiparesis and Brain Lesions Requiring a Diagnostic Brain Biopsy

We report a case of a 20-month-old girl with atypical presentation of a fairy common condition. She presented with acute onset of fever, seizures and hemiparesis. Her cerebrospinal fluid (CSF) showed total nucleated cells 10/mm3 with lymphocyte dominance. Herpes simplex virus (HSV) polymerase chain reaction (PCR) result was negative. Computed tomography (CT) of head showed a cerebral hemorrhage of the left frontal lobe and small subarachnoid hemorrhage in right frontal region. Brain MRI revealed multiple foci of hyperintensity in bilateral parietal lobes and right basal ganglia.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research