Hypertension: Quarter dose quadpill combinations: a new therapeutic approach
Nature Reviews Nephrology 13, 266 (2017). doi:10.1038/nrneph.2017.45 Authors: Guido Grassi &Giuseppe Mancia Achieving optimal blood pressure with antihypertensive agents in hypertensive patients can be particularly challenging. A major factor in this challenge is poor implementation of and compliance with multidrug regimens. However, a recent study shows encouraging results with a new single pill product that contains ultra-low doses of four antihypertensive agents.
Authors: Dhont S, de Niel C, van Mieghem C PMID: 31536466 [PubMed - as supplied by publisher]
Conclusion: We identified the physicians' prescription patterns of antihypertensive drugs for treatment-naïve patients. The findings of this study can lead to a rational, evidence-based, and cost-effective improvement of prescription patterns in newly diagnosed hypertensive patients. PMID: 31534797 [PubMed]
Authors: Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R Abstract Abnormal pulmonary arterial vascular smooth muscle cells (PASMCs) proliferation is critical pathological feature of pulmonary vascular remodeling that acts as driving force in the initiation and development of pulmonary arterial hypertension (PAH), ultimately leading to pulmonary hypertension. Aloperine is a main active alkaloid extracted from the traditional Chinese herbal Sophora alopecuroides and possesses outstanding antioxidation and anti-inflammatory effects. Our group found Aloperine has protective effects on monocroline-induced p...
Conclusion: In healthy pregnancy, we reported CIMT was related to BMI and maternal age but not parity or gestational age. PMID: 31535936 [PubMed - as supplied by publisher]
Conclusions: Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia. PMID: 31530202 [PubMed - as supplied by publisher]
Authors: Szmuda T, Kierońska S, Słoniewski P, Dzierżanowski J Abstract Introduction: Standard craniotomy (SC) and burr hole craniostomy (BHC) are regarded as the standard approaches to chronic subdural haematoma (CSDH). Bedside twist drill craniostomy (TDC), performed at the patient's bedside, was introduced as an alternative to the standard methods. However, clinical and radiological features of patients treated with TDC and BHC/SC have not been compared. Aim: To demonstrate the specific features of CSDH that affect the surgeons' preferences when selecting patients for TDC. Material and methods: A retro...
HIGH blood pressure is a common condition which can be hard to spot because symptoms don ’t always show, but left untreated it can lead to serious and life-threatening complications. Eating a certain soup could help control or prevent a high reading.
Conclusions: There is a risk of leptospira infections having a late diagnosis given their unspecific clinical presentation, which generates a high number of differential diagnoses. The early management in the intensive care unit could decrease the incidence of complications and the mortality of patients with leptospirosis. PMID: 31529853 [PubMed - in process]
Publication date: Available online 18 September 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yahia Zaid, Abbas Rajeh, Saeed Hosseini Teshnizi, Ali Alqarn, Firoozeh Tarkesh, Zahra Esmaeilinezhad, Reza NikandishAbstractBackground/objectiveStroke is the second leading cause of death globally that predisposed to sepsis. Therefore, this study was aimed to assess the risk factors and epidemiologic features of sepsis in ischemic stroke patients admitted to ICUs.MethodsThroughout this prospective study, we investigated all severe ischemic stroke patients admitted to ICUs of Namazi and Ali-Ashghar Hospitals in Shiraz. Aft...
CONCLUSION: VZV infection should be suspected in any patient with signs and symptoms of viral meningitis or encephalitis, irrespective of age, immune status, presence or absence of vesicles, fever, or neck stiffness. PMID: 31526545 [PubMed - as supplied by publisher]