Glomerular disease: mTOR in FSGS

Nature Reviews Nephrology 13, 260 (2017). doi:10.1038/nrneph.2017.42 Author: Susan J. Allison Progression of focal segmental glomerulosclerosis (FSGS) is associated with podocyte loss and hypertrophy of remaining podocytes; however, the mechanisms underlying these processes are unknown. New findings reveal a role for mTORC1 in balancing glomerular maintenance and disease progression in FSGS. “Complete mTOR inhibition or mTOR
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research