Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats

Disturbances in coronary microcirculatory function, such as the endothelial glycocalyx, are early hallmarks in the development of obesity and insulin resistance. Accordingly, in the present study myocardial mi...

Source: Cardiovascular Diabetology - April 11, 2017 Category: Cardiology Authors: Judith van Haare, M. Eline Kooi, Jurgen W. G. E. van Teeffelen, Hans Vink, Jos Slenter, Hanneke Cobelens, Gustav J. Strijkers, Dennis Koehn, Mark J. Post and Marc van Bilsen Source Type: research