Diverging effects of diabetes mellitus in patients with peripheral artery disease and abdominal aortic aneurysm and the role of advanced glycation end-products: ARTERY study -- protocol for a multicentre cross-sectional study

This study is approved by the Medical Ethics committees of University Medical Center Groningen, Martini Hospital and Medisch Spectrum Twente, the Netherlands. Study results will be disseminated through peer-reviewed journals and scientific events. Trial registration number trialregister.nl NTR 5363.
Source: BMJ Open - Category: Journals (General) Authors: Tags: Open access, Cardiovascular medicine, Diabetes and Endocrinology Protocol Source Type: research

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Publication date: Available online 16 September 2019Source: Academic RadiologyAuthor(s): Mohammad Hadi Bagheri, Holger Roth, William Kovacs, Jianhua Yao, Faraz Farhadi, Xiaobai Li, Ronald M. SummersPurposeAccurate pancreas segmentation has application in surgical planning, assessment of diabetes, and detection and analysis of pancreatic tumors. Factors that affect pancreas segmentation accuracy have not been previously reported. The purpose of this study is to identify technical and clinical factors that adversely affect the accuracy of pancreas segmentation on CT.Method and MaterialsIn this IRB and HIPAA compliant study, ...
Source: Academic Radiology - Category: Radiology Source Type: research
This study is a prospective, exploratory, qualitative analysis. Twenty midwives from Grenoble Alpes University Hospital who took care of one of the selected patients participated in this study. Two women had schizophrenia and one bipolar disorder. Interviews realized with a semi-structured guide were fully transcribed, anonymized and thematically analyzed. Topics have been structured according to the number of occurrences to build a thematic tree. RESULTS: Midwives felt insecure and resourceless when the postpartum care was unclear, insufficiently anticipated and in case of a danger for the women or the children. They ...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
Abstract Leptin, an adipokine that is implicated in the control of food intake via appetite suppression, may also stimulate oxidative stress, inflammation, thrombosis, arterial stiffness, angiogenesis and atherogenesis. These leptin-induced effects may predispose to the development of cardiovascular diseases. In the present review we discuss the evidence linking leptin levels with the presence, severity and/or prognosis of both coronary artery disease and non-cardiac vascular diseases such as stroke, carotid artery disease, peripheral artery disease (PAD) and abdominal aortic aneurysms (AAA) as well as with chroni...
Source: Acta Pharmacologica Sinica - Category: Drugs & Pharmacology Authors: Tags: Acta Pharmacol Sin Source Type: research
CONCLUSIONS: Risk factors associated with long-term mortality following elective EVAR remain scarcely published. Several demographic, anatomical, cardiovascular, pulmonary and renal co-morbidities seem to have an association with long-term mortality. Critical scrutiny of clinical patient status remains fundamental for a fair health resources allocation. PMID: 29745617 [PubMed - as supplied by publisher]
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
Purpose of review: Adiponectin is an adipokine with anti-inflammatory, antioxidant, antiatherogenic, pro-angiogenic, vasoprotective and insulin-sensitizing properties. Several factors may influence adiponectin levels, such as genetic polymorphisms, obesity / body fat distribution, diet and exercise as well as cardiovascular risk factors such as sleep deprivation and smoking as well as medications. Adiponectin has been proposed as a potential prognostic biomarker and a therapeutic target in patients with cardiometabolic diseases. Recent findings: This narrative review discusses the associations of adiponectin with obesity-...
Source: Current Opinion in Lipidology - Category: Lipidology Tags: HYPERLIPIDAEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research
The objective of this study was to examine the benefits of using CAVI as a predictor of cardiovascular events in high-risk patients.Methods and Design: This prospective multicenter study to evaluate the usefulness of the CAVI to predict cardiovascular events in Japan (CAVI-J) is a cohort study with central registration. Participants (n = 3,000) will be scheduled to enroll and data will be collected for up to 5 years from entry of participants into the study. To be eligible to participate in the CAVI-J study, individuals have to be aged between 40 and 74 years and have at least one of the following risk factors for arterios...
Source: Pulse - Category: Cardiology Source Type: research
Both coronary artery and peripheral artery disease are representative atherosclerotic diseases, which are positively associated with presence of abdominal aortic aneurysm. Diabetes mellitus that is one of major risk factors of coronary artery and peripheral artery diseases, however, has been curiously suggested to be negatively associated with abdominal aortic aneurysm in spite of the positive associations of coronary artery and peripheral artery diseases with presence of abdominal aortic aneurysm.
Source: Seminars in Vascular Surgery - Category: Surgery Authors: Source Type: research
Both coronary artery and peripheral artery disease are representative atherosclerotic diseases that are positively associated with presence of abdominal aortic aneurysm (AAA). Diabetes mellitus, which is one of major risk factors of coronary artery and peripheral artery diseases, however, has been curiously suggested to be negatively associated with AAA, despite the positive associations of coronary artery and peripheral artery diseases with presence of AAA. In the present article, we overviewed epidemiologic evidence (meta-analyses) regarding the associations of diabetes mellitus with presence, expansion, and rupture of A...
Source: Seminars in Vascular Surgery - Category: Surgery Authors: Source Type: research
Hypertension is a major risk factor for cardiovascular disease in the elderly.1 Hypertension occurs in 69% of persons with a first myocardial infarction,2 in 77% of those with a first stroke,2 in 74% of individuals with congestive heart failure,2 and in 60% of older adults with peripheral artery disease.3 Hypertension is also a major risk factor in older adults for dissecting aortic aneurysm, sudden cardiac death, angina pectoris, chronic kidney disease, left ventricular hypertrophy, thoracic and abdominal aortic aneurysms, atrial fibrillation, diabetes mellitus, the metabolic syndrome, vascular dementia, Alzheimer disease...
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Editorial Source Type: research
Conclusions Presence of cardiovascular disease, hypertension, hypercholesterolemia, and diabetes in offspring, with diabetes mellitus being the most contributing cardiovascular risk factor, is related to an increased risk of developing new or subsequent vascular events in patients already at high vascular risk.
Source: American Heart Journal - Category: Cardiology Source Type: research
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