Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors

Conclusions We propose that high circulating IL-8 in human alcoholic hepatitis may cause pathogenic overzealous neutrophil activation, and therapeutic blockade via pepducins merits clinical study.

http://gut.bmj.com/cgi/content/short/66/5/930?rss=1

Source: Gut - April 7, 2017 Category: Gastroenterology Authors: Wieser, V., Adolph, T. E., Enrich, B., Kuliopulos, A., Kaser, A., Tilg, H., Kaneider, N. C. Tags: Alcoholic liver disease, Hepatitis other, Open access Hepatology Source Type: research