Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department. Meyering, Stefan H; Stringer, Ryan W; Hysell, Matthew K

Abstract Introduction: Headaches represent over 3 million Emergency Department visits per year comprising 2.4 percent of all ED visits. Headaches are thought to be one of the three most common complaints of patient presentations to EDs across the country. There are many proposed methods and clinical guidelines of treating acute headache presentations however data on intravenous acetaminophen usage in these settings are lacking.   Objectives: The study attempts to determine the efficacy of IV Acetaminophen as an adjunct to a standard therapy for the treatment of patients who present to the emergency department with a chief complaint of “headache” or variants thereof.   Design: Randomized, double-b lind, placebo-controlled trial. Institutional IRB approval was obtained prior to implementation.   Setting: Academic Community Hospital.   Patients: Key elements of eligibility included adults ages 18-65 who had n...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research