Role of acid sphingomyelinase and IL-6 as mediators of endotoxin-induced pulmonary vascular dysfunction

Conclusions
Our data indicate that aSMase and IL-6 are not simply biomarkers of poor outcomes but pathogenic mediators of pulmonary vascular dysfunction in ARDS secondary to Gram-negative infections.

Source: Thorax - April 10, 2017 Category: Respiratory Medicine Authors: Pandolfi, R., Barreira, B., Moreno, E., Lara-Acedo, V., Morales-Cano, D., Martinez-Ramas, A., de Olaiz Navarro, B., Herrero, R., Lorente, J. A., Cogolludo, A., Perez-Vizcaino, F., Moreno, L. Tags: Respiratory research Source Type: research