PodMed – Week of April 10, 2017

This week’s topics include weight and mortality, normal BMI and cardiovascular risk factors, flu vaccination and mortality in kids, and an increased incidence of thyroid cancer. Program notes: 0:35 Flu vaccination and death in children 1:35 About a fourth of the kids who died had been vaccinated 2:44 Mortality and body weight 3:45 Over 32,000 […]
Source: Johns Hopkins Medicine Weekly Health News - Category: Consumer Health News Authors: Tags: All Podcasts Cancer Heart And Vascular Infectious diseases Obesity Pediatrics PodMed Vaccines Source Type: podcasts

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Conclusion: Regional differences in radiation dose were not associated with increased risk of thyroid cancer among children in Fukushima within 4 to 6 years after the nuclear power plant accident. Obesity may be an important factor for further follow-up in Fukushima.
Source: Epidemiology - Category: Epidemiology Tags: Cancer Source Type: research
P, Truong T Abstract Despite research efforts, current knowledge on the etiology of thyroid carcinoma remains limited. To explore the potential role of diet-induced inflammation, we examined the association between differentiated thyroid cancer risk and the energy-adjusted Dietary Inflammatory Index (E-DII®) in a population-based case-control study conducted in New Caledonia - a Pacific archipelago with one of the highest recorded thyroid cancer incidence rates in the world. The E-DII was computed from food frequency questionnaire information on usual dietary intake. Logistic regression analyses were performed...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research
CONCLUSIONS: Women with CTEPH underwent PEA less frequently than men, especially at low-volume centers. Furthermore, they had a lower prevalence of cardiovascular risk factors and were less often exposed to additional cardiac surgery procedures. Women had better long-term survival. This article is protected by copyright. All rights reserved. PMID: 31479557 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Tags: J Thromb Haemost Source Type: research
Purpose of review Compared with adults, there is a two-fold to three-fold increased risk of malignancy for a pediatric patient undergoing evaluation of a thyroid nodule. In 2015, the American Thyroid Association published guidelines on the evaluation and management of pediatric patients with thyroid nodules and differentiated thyroid cancer. The goal of this clinical update is to review recent additions to the literature and propose opportunities how to best incorporate these findings into clinical practice. Recent findings Recent additions to the literature include assessment of ultrasound-based scoring systems to im...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - Category: Endocrinology Tags: THYROID: Edited by Angela M. Leung Source Type: research
Purpose of review Our understanding of the molecular pathology events involved in thyroid cancer initiation and progression and its subtypes has markedly improved as a result of multiomic studies. Recently, long noncoding RNA (lncRNA) have been shown to have a role in cancer initiation and progression and have also been studied in thyroid cancer. Recent findings lncRNA are dysregulated in thyroid cancer. lncRNA have tumor suppressive and oncogenic function in thyroid cancer cells and play a role in some of the established genetic drivers of thyroid cancer initiation and progression. Lastly, some lncRNA are associated ...
Source: Current Opinion in Endocrinology, Diabetes and Obesity - Category: Endocrinology Tags: THYROID: Edited by Angela M. Leung Source Type: research
AbstractHelicobacter pylori (H. pylori) infection is a common disease that can cause chronic gastritis, peptic ulcers, and gastric cancer. Nevertheless, due to its ability to elicit a systemic inflammatory response, it has also been related to several extra-gastric manifestations including endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus, dyslipidemia, and obesity.H. pylori infection has also been linked to osteoporosis, although currently available data are equivocal. This brief review will focus on the possible association betweenH. pylori infection and osteoporosis, a silent disease characteri...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Minho Shong Bon Seok Koo Fibroblast growth factor 21 (FGF21) plays important roles in regulating glucose, lipid, and energy metabolism; however, its effects in tumors remain poorly understood. To understand the role of FGF21 in regulating tumor aggressiveness in thyroid cancer, serum levels of FGF21 were measured in healthy subjects and patients with papillary thyroid cancer (PTC), and expression levels of FGF21, FGF receptors (FGFRs), and β-klotho (KLB) were investigated in human thyroid tissues. The cell viability, migrating cells, and invading cells were measured in PTC cells after treatment with recombi...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Publication date: 15 September 2019Source: Life Sciences, Volume 233Author(s): Ke Wang, Xiang-hua Yu, Ya-Jie Tang, Ya-ling Tang, Xin-hua LiangAbstractObesity has become pandemic and emerged as one of the most critical global health care problems worldwide since last century. Recent studies have demonstrated that there may be a causal link between obesity and higher risks and mortality of cancers, including prostate, breast, colon, and thyroid cancers, head and neck cancer (HNC). This review focuses on the relationship between obesity and HNC, and the molecular mechanism of abnormal lipid metabolism in HNC. Elucidating the ...
Source: Life Sciences - Category: Biology Source Type: research
CONCLUSION: Surgery time, female gender, repeated dissection and total thyroidectomy for benign adenoma are risk factors that should be considered in decision-making for performing TT on an outpatient basis. PMID: 31400860 [PubMed - as supplied by publisher]
Source: Annales d'Endocrinologie - Category: Endocrinology Authors: Tags: Ann Endocrinol (Paris) Source Type: research
AbstractThe field of thyroid hormone signaling has grown more complex in recent years. In particular, it has been suggested that some thyroid hormone derivatives, tentatively named “novel thyroid hormones” or “active thyroid hormone metabolites”, may act as independent chemical messengers. They include 3,5-diiodothyronine (T2), 3-iodothyronamine (T1AM), and several iodothyroacetic acids, i.e., 3,5,3’,5’-thyroacetic acid (TA4), 3,5,3’-thyroacetic acid (TA3), and 3 -thyroacetic acid (TA1). We summarize the present knowledge on these compounds, namely their biosynthetic pathways, endo...
Source: Endocrine - Category: Endocrinology Source Type: research
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