Pediatric Myasthenia Gravis

Myasthenia gravis is a disorder of neuromuscular transmission which leads to fatigue of skeletal muscle and fluctuating weakness. Myasthenia that affects children can be classified as one of three forms: transient neonatal myasthenia, the congenital myasthenic syndromes, and juvenile myasthenia gravis. Juvenile myasthenia gravis is an autoimmune disorder that has a tendency to affect the extraocular muscles, but can affect all skeletal muscles leading to generalized weakness and fatigability. The muscles involved in respiration can be involved leading to respiratory failure requiring ventilator support.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Tags: Pediatric Neuro-Ophthalmology Source Type: research