Perceptions of Parkinson's Disease
' People think I'm drunk but I have Parkinson's 'By Lindsay BrownBBC Newsbeat reporter10 April 2017Read report here [snip]" Jordan was diagnosed with Parkinson's when he was 17 and says people often think he's had too much to drink. " [snip]
CONCLUSIONS: despite increasing evidence that tDCS may improve motor symptoms, the results showed that fully optimized tDCS protocols are not yet established. PMID: 31821532 [PubMed - in process]
CONCLUSION: The results suggest that the efficiency of applied cognitive strategy behaviours is compromised in a certain pattern in people with Parkinson's disease, and that it declines with disease progression. PMID: 31820814 [PubMed - as supplied by publisher]
New research in mice and flies suggests that failure to transport molecules that break down proteins in neurons may lead to neurodegenerative diseases.
Condition: Parkinson Disease Intervention: Other: Non pharmacological therapy Sponsor: Puerta de Hierro University Hospital Recruiting
Abstract Neurological diseases particularly Alzheimer's disease (AD), Parkinson's disease (PD), stroke, and epilepsy are on the rise all around the world causing morbidity and mortality globally with a common symptom of gradual loss or impairment of motor behaviour. Striatum, which is a component of the basal ganglia, is involved in facilitating voluntary movement while the cerebellum is involved in the maintenance of balance and coordination of voluntary movements. Dopamine, serotonin, gamma-aminobutyric acid (GABA), and glutamate, to name a few, interact in regulating the excitation and inhibition of motor neuro...
Objective biomarkers are required for differential diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP).
The aim of the present study was to investigate the potential predictors of subjectively reported swallowing impairment in a cohort of early-stage and drug na ïve Parkinson's disease patients.
Bladder dysfunction may cause disabling symptoms in Parkinson's disease (PD) patients. The majority patients' experience symptoms as urinary urgency and nocturia suggest overactive bladder. This seems to be due to an altered brain –bladder relationship because of alteration in fronto-basal ganglia D1-dopaminergic circuit that normally suppresses micturition-reflex. Previous studies demonstrated beneficial effect of D1/D2 dopamine-receptors chronic-stimulation on detrusor overactivity of PD-patients.The present study was aim ed to evaluate possible effect of extended-release (ER) Levodopa administered at bed-time on b...
ConclusionThe quality of RCTs in functional neurosurgery has improved over time but reporting of specific metrics such as power calculations and allocation concealment requires further improvement. Device approval status but not funding source was associated with trial quality.
Sensors, Vol. 19, Pages 5468: Cueing Paradigms to Improve Gait and Posture in Parkinson’s Disease: A Narrative Review Sensors doi: 10.3390/s19245468 Authors: Niveditha Muthukrishnan James J. Abbas Holly A. Shill Narayanan Krishnamurthi Progressive gait dysfunction is one of the primary motor symptoms in people with Parkinson’s disease (PD). It is generally expressed as reduced step length and gait speed and as increased variability in step time and step length. People with PD also exhibit stooped posture which disrupts gait and impedes social interaction. The gait and posture impairments are u...