Overlapping features of polymyositis and inclusion body myositis in HIV-infected patients
Conclusions:
HIV-positive patients with myositis may present with some characteristic polymyositis features including young age at onset, very high CK levels, or proximal weakness that improves with treatment. However, all HIV-positive patients with myositis eventually develop features most consistent with inclusion body myositis, including finger and wrist flexor weakness, rimmed vacuoles on biopsy, or anti-NT5C1A autoantibodies.
Source: Neurology - Category: Neurology Authors: Lloyd, T. E., Pinal-Fernandez, I., Michelle, E. H., Christopher-Stine, L., Pak, K., Sacktor, N., Mammen, A. L. Tags: HIV, Muscle disease ARTICLE Source Type: research