Correction

Williams J, Hagger-Johnson G. Childhood academic ability in relation to cigarette, alcohol and cannabis use from adolescence into early adulthood: Longitudinal Study of Young People in England (LSYPE). BMJ Open 2017;7:e012989. doi: 10.1136/bmjopen-2016-012989 There are some errors in the RR and 95% CI values in the Results paragraph of the Abstract. This paragraph should read as follows: Results In multinomial logistic regression models adjusting for a range of covariates, the high (vs low) academic ability reduced the risk of persistent cigarette smoking (RR=0.62; CI 95% 0.48 to 0.81) in early adolescence. High (vs low) academic ability increased the risk of occasional (RR=1.25; CI 95% 1.04 to 1.51) and persistent (RR=1.83; CI 95% 1.50 to 2.23) regular alcohol drinking in early adolescence and persistent (RR=2.28; CI 95% 1.84 to 2.82) but not occasional regular alcohol drinking in late adolescence. High (vs low) academic ability was also positively associated with...
Source: BMJ Open - Category: Journals (General) Authors: Tags: 1506 Source Type: research

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Publication date: 1 December 2019Source: Materials Letters, Volume 256Author(s): P. Ramesh, S. Sambathkumar, R. Jagatheesan, S. Vasanth KumarAbstractIn this case, a facile synthesis of alcohol functionalized graphene oxide (GO) material has been made using water soluble, non-toxic, biocompatible tris buffer (TB) and diethenolamine (DEA). This functional material was characterized by various techniques such as, XRD, TEM, XPS, Raman, TGA and Cyclic voltametry (CV). The molecular level grafting of amines to graphene has been occurred due to the functionalization of alcohol by the enlargement of interlayer spacing and specific...
Source: Materials Letters - Category: Materials Science Source Type: research
Abstract 1-Chloro-2-hydroxy-3-butene (CHB) is a possible metabolite of 1,3-butadiene, a carcinogenic air pollutant. To demonstrate its formation in vivo, it is desirable to develop a practical biomarker and the corresponding analysis method. CHB can undergo alcohol dehydrogenase- and cytochromes P450 enzymes (P450)-mediated oxidation to yield 1-chloro-3-buten-2-one (CBO), which readily forms glutathione conjugates. We hypothesized that CBO-derived mercapturic acids, which are the expected biotransformed products of CBO-glutathione conjugates, could be used as CHB biomarkers. Thus, in the present study, we investig...
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
The review found that people who had a bit of alcohol daily had lower levels of a type of blood fat called triglycerides. But alcohol didn't seem to lower blood sugar levels in people who already had type 2 diabetes, the review found.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Publication date: 15 January 2020Source: Journal of Molecular Structure, Volume 1200Author(s): Salih Paşa, Nevin Arslan, Nermin Meri̇ç, Cezmi Kayan, Murat Bingül, Feyyaz Durap, Murat AydemirAbstractAsymmetric Transfer Hydrogenation (ATH) has been an attractive way for the reduction of ketones to chiral alcohols. A great number of novel and valuable synthetic pathways have been achived by the combination usage of organometallic and coordination chemistry for the production of important class of compounds and particularly optically active molecules. For this aim, four boron containing Schiff bases were synthesi...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 17 September 2019Source: Carbohydrate PolymersAuthor(s): Sweetie R. Kanatt, Sweta H. MakwanaAbstractThe potential of citric acid (CA) included as a crosslinker for development of CMC-PVA films with better mechanical and lower solubility was examined. To make functional active packaging films for storage of perishable food products, the role of Aloe vera (AV) was also investigated. Addition of CA effectively improved the mechanical properties, reduced the water solubility, moisture content and water vapour permeability of the film. FTIR analysis confirmed that incorporation of CA led to fo...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Authors: Johnston MP, Patel J, Byrne CD Abstract Introduction The pandemic of obesity over the last two decades has triggered a rise in prevalence of non-alcoholic fatty liver disease (NAFLD). NAFLD is associated with liver-related- and cardiovascular complications. Despite this, the first licensed drug for NAFLD is yet to be approved. Given the scale of the problem and unmet needs, there is a myriad of agents in the development pipeline. Areas covered We discuss promising agents in early phase clinical trials and categorize these agents based on their action on steatosis, steatohepatitis and fibrosis. Furthermore,...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
Authors: Westerouen van Meeteren MJ, Drenth JPH, Tjwa ETTL Abstract Introduction: Non-alcoholic fatty liver disease (NAFLD) encompasses a progressive disease phenotype starting from simple steatosis, which can progress to nonalcoholic steatohepatitis (NASH). It is component of the metabolic syndrome with a large impact on mortality in these patients. PPARs are nuclear receptors that regulate lipid and insulin metabolism, two key components in pathophysiology of NAFLD and NASH. Elafibranor acts as an agonist of PPAR-α and PPAR-δ and is currently under development for the treatment of NAFLD. Areas covered...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
The purpose of the present study was to determine whether dating violence victimization (psychological, physical, and sexual) and substance use (alcohol and marijuana) predicted sexual behaviors that increase risk for poor outcomes from ages 15-19. Adolesc...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
WEDNESDAY, Sept. 18, 2019 -- Four modifiable risk factors -- body mass index (BMI), the Dietary Approaches to Stop Hypertension (DASH) diet, alcohol use, and diuretic use -- could individually account for a notable proportion of hyperuricemia and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Contributors : Sangwon Byun ; Sunmi Seok ; Young-Chae Kim ; Yang Zhang ; Peter Yau ; Naoki Iwamori ; H E Xu ; Matthew J Potthoff ; Jian Ma ; Byron Kemper ; Jongsook K KemperSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAutophagy is essential for cellular survival and energy homeostasis under nutrient deprivation. Despite the emerging importance of nuclear events in autophagy regulation, epigenetic control of autophagy gene transcription remains unclear. Here, we identify Jumonji-D3 (JMJD3/KDM6B) histone demethylase as a key epigenetic activator of hepatic autophagy. Upon fasting-ind...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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