Dysregulation of LncRNAs in placenta and pathogenesis of preeclampsia.

This article reviews published data on this subject and provides detailed information on the regulation and function of LncRNAs IGF2/H19, MEG3, SPRY4-IT1, HOTAIR, MALAT1, and FLT1P1 and CEACAMP8 in placental trophoblasts. The potential mechanisms underlying the action of these LncRNAs are also discussed to facilitate a better understanding on the potential role of these LncRNAs for the pathogenesis of preeclampsia. PMID: 28382860 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28382860?dopt=Abstract

Source: Current Drug Targets - April 4, 2017 Category: Drugs & Pharmacology Authors: Song X, Luo X, Gao Q, Wang Y, Gao Q, Long W Tags: Curr Drug Targets Source Type: research