A Case of Multiple System Atrophy with Preexisting Alzheimer's Disease and Predating The Hot Cross Bun Sign.

CONCLUSION: Given that the HCB sign rarely predates overt symptoms or a diagnosis of MSA, we hypothesized that the preexisting amyloidopathy and tauopathy exerted additional neurotoxicity on the synucleinopathy. Key Words: Multiple system atrophy, hot cross bun sign, Alzheimer's disease. PMID: 28382615 [PubMed - in process]
Source: Acta Neurologica Taiwanica - Category: Neurology Tags: Acta Neurol Taiwan Source Type: research