Molecular diagnosis in children with fractures but no extraskeletal signs of osteogenesis imperfecta
ConclusionsDNA sequence analysis of currently known OI-associated genes identified disease-causing variants in more than a quarter of individuals with a significant fracture history but without extraskeletal manifestations of OI.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
More News: Children | Genetics | Orthopaedics | Osteogenesis Imperfecta (brittle bone disease) | Osteoporosis