Hypothalamic Hamartoma with Infantile Spasms: Case Report with Surgical Treatment

We report a 10 month-old boy with treatment-resistant infantile spasms associated with hypothalamic hamartoma (HH). EEG prior to surgical treatment showed modified hypsarrhythmia. Transventricular endoscopic resection and disconnection resulted in immediate and enduring disappearance of the epileptic spasms and improvement in the post-operative EEG. Eight years after treatment the patient has non-disabling gelastic seizures associated with a small amount of residual HH but no other seizure types.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research