Expression of Filaggrin and its Degradation Products in Human Skin Following Erythemal Doses of Ultraviolet B Irradiation.

In conclusion, erythemal doses of ultraviolet B exert acute effects on profilaggrin mRNA and filaggrin protein in human skin in vivo. PMID: 28358172 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research

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Anecdotally some dermatologists I've talked to would set up a separate "procedure only day." Many PCPs in my area who perform biopsies already schedule separate "procedure visits" for biopsies. This has the following ethical considerations: 1. Patients may need to take extra time off work (2 days instead of 1 day). 2. While most would (probably correctly) argue that delaying a biopsy by
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Dermatology Source Type: forums
CONCLUSIONS: Genitourinary skin metastasis are rareand have poor prognosis. The largest incidence is in renaltumors, followed by bladder and prostate malignancies. PMID: 31697260 [PubMed - in process]
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
Many psoriasis patients treated with biologics do not achieve total skin clearance. These patients possess “residual plaques” despite ongoing biologic treatment. To elucidate mechanisms of plaque persistence despite overall good drug response, we studied fifty subjects: psoriasis patients with residual plaques treated with one of three different biologics, untreated patients, and healthy controls. Sk in biopsies from all subjects were characterized using three methods: mRNA expression, histology, and FACS of skin hematopoietic cells.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
Conclusion: Depressed soft tissue and skin folds on ischial areas were significantly improved by volumization of subdermal filler injection. The skin quality, roughness, and pigmentation on ischial areas improved, and these improvements may be caused by intradermal micro-droplet injections of CaHA filler which may be influenced by neocollagenesis by numerous fibroblasts and increased micro-blood circulation (neovascularization). This is the first article to show the scientific evidence of neocollagenesis and tissue reaction after an injection of CaHA filler in the dermis, especially using various histological staining and ...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
Authors: Sorour NE, Hamed AM, Tabl HAM, Ahmed AAA Abstract Background: Common warts are caused by human papillomaviruses (HPVs), they are among the most common cutaneous viral infections. Macrophage migration inhibitory factor (MIF) is an essential contributor in many inflammatory and immune skin diseases. Yet, its role in the pathology of common warts is unclear. Objective: To assess MIF levels in lesional and perilesional skin in patients with common warts in comparison to apparently healthy control group with matching age and sex. Subjects and methods: A case-control study performed on 60 patients with c...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
Publication date: Available online 7 November 2019Source: Parasitology InternationalAuthor(s): Luca Villa, Alessia Libera Gazzonis, Chiara Perlotti, Sergio Aurelio Zanzani, Giuseppe Sironi, Maria Teresa ManfrediAbstractA form of generalized demodectic mange in two dairy cows infected with Besnoitia besnoiti is described. The herd was endemically infected with bovine besnoitiosis; an overall seroprevalence of B. besnoiti antibodies of 23.5%, that increased up to 43.5% considering only cows, was reported. Two out of the cows seropositive to B. besnoiti, at clinical examination presented skin nodules, widespread all over the ...
Source: Parasitology International - Category: Parasitology Source Type: research
ConclusionsNew clinical aspect of diffuse alveolar hemorrhage is first reported to be associated with SAVI. Unsatisfactory therapeutic effects of tofacitinib are observed in this study and further evaluations are needed.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
ConclusionsAssuming moderate differences in accuracy with systematic screening versus usual care, screening for melanoma every 2 years starting at age 50 or 60 may be cost-effective in white men. Results are sensitive to degree of difference in sensitivity with screening compared to usual care. Better studies of the accuracy of systematic screening exams compared with usual care are required to determine whether a trial of screening should be undertaken.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
ConclusionOur findings suggest that combination chemotherapy plus bevacizumab is an effective therapeutic option in patients with cutaneous lymphangitis carcinomatosa arising from cervical cancer.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conclusion: The expression of CD3, CCR4, and CCR10 on cells present in PD lesions could indicate that T-lymphocytes are recruited to the site of inflammation by chemokine–chemokine receptor interactions and hence provide evidence for the response by the adaptive immune system following a PD.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
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