Endocrine Society, Medscape partner to bring endocrine expertise to clinicians worldwide

(The Endocrine Society) The Endocrine Society and Medscape announced today a new partnership that brings together the Society's expertise and Medscape's innovative, peer-to-peer digital platforms and award-winning content to provide clinicians with the latest guidance and most relevant insights on diagnosing and treating diabetes, obesity, osteoporosis, infertility, and other endocrine disorders.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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Source: BMJ Comments - Category: General Medicine Source Type: forums
In this study, we screened 110 Taiwanese children (61 males and 49 females) with T1D onset before the age of 5 years for mutations of INS and KCNJ11. We identified one missense heterozygous mutation in KCNJ11 (c.989A>G, p.Y330C) and no INS mutations among 28 probands. This is the first study to screen patients with autoantibody-negative T1D diagnosed before the age of 5 years for INS and KCNJ11 mutations in Taiwan. Although KCNJ11 mutations are always reported in patients with permanent neonatal diabetes, this gene mutation can be detected after 6 months of age. Further studies in other patients with type 1B diabetes an...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Publication date: August 2018Source: Journal of the Formosan Medical Association, Volume 117, Issue 8Author(s): Yi-Chih Lin, Yu-Hsing Chang, Shao-Yu Yang, Kwan-Dun Wu, Tzong-Shinn ChuDiabetic kidney disease (DKD) is a major cause of morbidity and mortality in patients with diabetes mellitus and the leading cause of end-stage renal disease in the world. The most characteristic marker of DKD is albuminuria, which is associated with renal disease progression and cardiovascular events. Renal hemodynamics changes, oxidative stress, inflammation, hypoxia and overactive renin-angiotensin-aldosterone system (RAAS) are involved in ...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Publication date: Available online 20 July 2018Source: International Journal of GerontologyAuthor(s): Ş.H. Aktaş, S. UcakSummaryBackgroundWith the ageing world population, osteoporosis becomes a major health issue. Vitamin and mineral deficiencies are the preventable causes of osteoporosis; and data regarding the effects of vit B12 deficiency on bone mineral density (BMD) remain conflicting. Consequently, we aimed to investigate the effects of vit B12 deficiency, which is common in patients older than 65 years of age, on osteoporosis.MethodsThis cross-sectional study was performed on 118 patients aged 65 and over who wer...
Source: International Journal of Gerontology - Category: Geriatrics Source Type: research
ConclusionsThe experimental results from the pharmacological research enable the validation of their traditional uses in several of the groups of diseases in the countries of origin and reveal these plants to be a valuable source for therapeutic molecules. However, more toxicity assays and clinical trials would be necessary to establish optimal and safe doses of consumption on the application of these medicinal plants.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: 1 November 2018Source: Materials Science and Engineering: C, Volume 92Author(s): Amir reza Ariamoghaddam, Bahman Ebrahimi-Hosseinzadeh, Ashrafalsadat Hatamian-Zarmi, Razi SahraeianAbstractObesity as a dominant problem in developed countries which is known to be basic step of so many diseases is subjected to find a solution for in this work. Curcumin containing polyvinyl alcohol-gelatin nanofibers which ranging from 200 to 250 nm in diameter as a transdermal drug delivery system for declining volume of subcutaneous adipose tissue is investigated here. Morphology and synthesis method of nanofibers is desi...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: 1 November 2018Source: Materials Science and Engineering: C, Volume 92Author(s): Richa Panwar, Navdeep Raghuwanshi, Amit Kumar Srivastava, Asvene K. Sharma, Vikas PruthiAbstractDiabetes mellitus (DM) is one of the most common lifestyle diseases, caused due to endocrine disorder. DM is commonly associated with hyperglycemia, a condition which is generally followed by an overproduction of free radicals leading to tissue oxidative stress. Currently, the focus of medical fraternity lies in developing therapeutic drugs based on natural origin in order to reduce the hyperglycemia associated toxicity. Ferulic ac...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
This study shows that lifespan-extending conditions can slow molecular changes associated with an epigenetic clock in mice livers. Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions Age-associated epigenetic changes are implicated in aging. Notably, age-associated DNA methylation changes comprise a so-called aging "clock", a robust biomarker of aging. However, while genetic, dietary and drug interventions can extend lifespan, their impact on the epigenome is uncharacterised. To fill this knowledge gap, we defined...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Discussion Klinefelter syndrome (KS) is a common genetic abnormaly with a prevalence of 1 in ~650 male births. It was first described in 1942 by Dr. Harry Klinefelter. It is associated with at least one extra X chromosome with the most common karyotype (~80% of patients) being 47 XXY. Other karyotypes are seen along with mosaicism. It is believed that although it is very prevalent, only about 25-33% of people with KS are identified. About 10% are identified before puberty with the rest usually identified because of hypogonadism and tall stature especially in teenage years or due to infertility in adulthood. KS is diagnosed...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Discussion Turner Syndrome (TS) is one of the most common genetic disorders in females. It was first described by Dr. Henry H. Turner in 1938. It affects 1 in 2000-2500 births and ~70,000 girls and women have TS in the United States. It is caused by the absence of all or part of the second X chromosome. The most common variation is 45X which affects about 50% of TS patients and usually has the most complications, but there are other variations. Phenotypes vary and therefore the age of diagnosis varies. Mean age of diagnosis unfortunately is 15 years. Diagnosis is made by chromosomal analysis. Haploinsufficiency of the SHOX...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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