Menopausal women become pregnant with their own eggs

Two women thought to be infertile have become pregnant using a technique that seems to rejuvenate ovaries. It is the first time such a treatment has enabled menopausal women to get pregnant using their own eggs.New Scientist
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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CONCLUSION: Our results show that Epstein-Barr infection is possibly associated with autoimmune ovarian failure. The devastating impact on fertility in such disorder can be successfully avoided by in vitro maturation of oocytes from excised ovarian tissue. PMID: 29618356 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Abstract It has been more than 15 years since the measurement of serum anti‐Müllerian hormone (AMH) first allowed the quantitative assessment of ovarian reserve. Meanwhile, the clinical implication of serum AMH has been expanding. The measurement of serum AMH has been applied in various clinical fields, including assisted reproduction, menopause, reproductive disorders and assessment of ovarian damage/toxicity. Well‐known findings about the usefulness of serum AMH revealed by numerous studies executed in the early era include decline with aging, a good correlation with oocyte yield in assisted reproduction, upregu...
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Authors: Tags: Invited Manuscript Source Type: research
Discussion regarding family planning is imperative in women with IBD with a strong recommendation to consider long-acting highly effective contraceptives such as intrauterine devices or implants. Cervical cancer screening should be tailored in women on immunosuppressive medications and all women under 26  years of age should be advised to receive the human papilloma virus vaccination.SummaryAs gastroenterologists will have longitudinal relationships with their female IBD patients, they must be knowledgeable about sex-specific issues during each stage of life from puberty to after menopause to optimize their patient ’s care.
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research
Conclusions Except for the risk of premature ovarian failure, a rare adverse effect of combined treatments, both single-agent and multiagent chemotherapy can be safely administered to patients with a desire for childbearing. High-risk patients have worse reproductive outcomes because they undergo hysterectomy more frequently than low-risk patients.
Source: International Journal of Gynecological Cancer - Category: Cancer & Oncology Tags: Gestational Cancer Source Type: research
Abstract ObjectiveTo compare the endocrinological profiles, cycle characteristics and pregnancy outcomes of progestin‐primed ovarian stimulation (PPOS) with or without clomiphene citrate (CC) supplementation in normal ovulatory women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). DesignProspective randomized controlled study. Patient(s)A total of 320 infertile women undergoing IVF/ICSI. Medroxyprogesterone acetate (MPA) and human menopausal gonadotropin (hMG) were simultaneously administered on menstrual cycle day 3. The women were randomized into two equal groups with or without CC supp...
Source: Clinical Endocrinology - Category: Endocrinology Authors: Tags: Original Article Source Type: research
Conclusion Using consensual knowledge lists might promote congruence in educating and/or training community pharmacists on women's issues in epilepsy. Future studies are needed to investigate if such lists can improve health services provided to women with epilepsy (WWE). Graphical abstract
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
CONCLUSION: Using consensual knowledge lists might promote congruence in educating and/or training community pharmacists on women's issues in epilepsy. Future studies are needed to investigate if such lists can improve health services provided to women with epilepsy (WWE). PMID: 29127865 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Fertility clinics, just like "anti-aging" clinics, are a lucrative niche industry that has the potential to stop being sketchy and fraud-ridden just as soon as reliable rejuvenation therapies arrive on the scene. Given this, one might view these and a number of other similar industries as potential pools of funding to help bring the first rejuvenation therapies to the clinic. That has to be balanced against the bad publicity attendant with doing business in this part of the market, but considered in the long run, if the therapies work then will even justifiable initial skepticism much matter? The Society for Resc...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Conclusion: This case highlights the complex interplay between ovarian steroids, depletion of their levels, and psychiatric sequelae. The postpartum period represents a particularly vulnerable time for patients with premature ovarian insufficiency, which requires very close monitoring and early replacement of depleted hormone levels.
Source: Menopause - Category: OBGYN Tags: Case Reports Source Type: research
Summary ObjectivesTo investigate the effects of low‐dose human chorionic gonadotropin (hCG) combined with human menopausal gonadotropin (HMG) protocol on cycle characteristics and outcomes of infertile women with hypogonadotropic hypogonadism (HH) undergoing ovarian stimulation for in vitro fertilization (IVF). DesignA retrospective cohort study. SettingTertiary‐care academic medical centre. Patient(s)Forty‐six infertile patients with HH and seventy‐one infertile patients with tubal factor (TF) infertility undergoing IVF. Intervention(s)In the study group, all 46 HH patients were given low‐dose hCG (50‐300IU/d)...
Source: Clinical Endocrinology - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
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