Log in to search using one of your social media accounts:


Swallowing Preparation and Execution: Insights from a Delayed-Response Functional Magnetic Resonance Imaging (fMRI) Study

AbstractThe present study sought to elucidate the functional contributions of sub-regions of the swallowing neural network in swallowing preparation and swallowing motor execution. Seven healthy volunteers participated in a delayed-response, go, no-go functional magnetic resonance imaging study involving four semi-randomly ordered activation tasks: (i) “prepare to swallow,” (ii) “voluntary saliva swallow,” (iii) “do not prepare to swallow,” and (iv) “do not swallow.” Results indicated that brain activation was significantly greater during swallowing preparation, than during swallowing execution, within the rostral and intermediate anterior cingulate cortex bilaterally, premotor cortex (left >  right hemisphere), pericentral cortex (left >  right hemisphere), and within several subcortical nuclei including the bilateral thalamus, caudate, and putamen. In contrast, activation within the bilateral insula and the left dorsolateral pericentral cortex was significantly greater in relation to swallowing execution, compared with swallowing preparation. Still other regions, including a more inferior ventrolateral pericentral area, and adjoining Brodmann area 43 bilaterally, and the supplementary motor area, were activated in relation to both swallowing preparation and execution. These findings support the view that the preparation, and subsequent execution, of swallowing are mediated by a cascading pattern of ac...
Source: Dysphagia - Category: Speech Therapy Source Type: research

Related Links:

Authors: Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K, Nishihara H, Hanaoka M, Sekijima Y Abstract A 49-year-old man presented with gradually progressive aphasia one month after being diagnosed with acquired immunodeficiency syndrome (AIDS). Brain magnetic resonance imaging showed multiple brain lesions with punctate and linear enhancement. A polymerase chain reaction detected Epstein-Barr virus (EBV) in the patient's cerebrospinal fluid. A diagnosis of isolated central nervous system lymphomatoid granulomatosis (CNS-LYG) was made based on the brain biopsy findings. The complete remission of CNS-LYG wa...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Authors: Daida K, Nishioka K, Li Y, Nakajima S, Tanaka R, Hattori N Abstract We herein report the case of a 47-year-old female with the colony-stimulating factor 1 receptor (CSF1R) mutation p.G589R, which is related to hereditary leukoencephalopathy with axonal spheroid (HDLS). The patient presented with an early-onset cognitive decline and progressive aphasia. Brain magnetic resonance imaging revealed HDLS-related alterations. In addition, brain computed tomography revealed interspersed spotty calcifications in the frontal and parietal subcortical white matter, while a characteristic "stepping stone" app...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
In this report, we present a case with remarkable shrinkage of a tumor after relatively short-term octreotide long-acting release (LAR) administration. During the 30-month follow-up after starting octreotide LAR, there was no recurrence of acromegaly with remarkable shrinkage of the tumor on pituitary magnetic resonance imaging. A literature review of the predictors for tumor shrinkage after the administration of somatostatin analogues in patients with acromegaly is also discussed in relation to this case. PMID: 28824054 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Abstract Hirayama's disease is a rare clinical variant of amyotrophic lateral sclerosis where distal muscles are involved more compared to proximal muscles and vice-versa occurs only in 10% cases and so it is differentiated from O'Sullivan McLeod syndrome which involves only small muscles of single limb. Here, we present a case of Hirayama's disease where disease achieved a plateau after 3 years with no further progression. His electrophysiological studies, and clinical picture, and magnetic resonance imaging findings were consistent with a diagnosis of Hirayama's disease. PMID: 28828346 [PubMed]
Source: Biomed Res - Category: Research Authors: Tags: Adv Biomed Res Source Type: research
ConclusionModeling the upper airway in OSA patients is feasible and holds promise in aiding patient‐specific surgical treatment. Level of EvidenceNA. Laryngoscope, 2017
Source: The Laryngoscope - Category: ENT & OMF Authors: Tags: Sleep Medicine Source Type: research
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study reviewed more than five years of records of pediatric patients treated for sports concussion, the most common form of traumatic brain injury (TBI) among children, to determine if magnetic resonance imaging (MRI) revealed structural changes to the brain that may be related to persistent symptoms.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusion: Low SI in the HBP of Gd-EOB-DTPA-MRI is associated with higher accuracy for distinguishing HCA from FNH. However, the diagnostic accuracy may be overvalued, especially for the diagnosis of subtypes of b-HCA and I-HCA. Therefore, the risk factors and conventional imaging findings should be take into account simultaneously. PMID: 28824299 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Park J, Park WY, Hong S, An J, Koh JC, Lee YW, Kim YC, Choi JB Abstract BACKGROUND: The Spurling test, although a highly specific provocative test of the cervical spine in cervical radiculopathy (CR), has low to moderate sensitivity. Thus, we introduced the neck tornado test (NTT) to examine the neck and the cervical spine in CR. OBJECTIVES: The aim of this study was to introduce a new provocative test, the NTT, and compare the diagnostic accuracy with a widely accepted provocative test, the Spurling test. DESIGN: Retrospective study. METHODS: Medical records of 135 subjects with neck pain (CR,...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Conclusions: Despite the obvious distinctions between orbital lymphoid tumors and lymphaticovenous malformations, several clinical radiologic specialists misdiagnosed the present orbital lesion as a vascular lesion. A combined clinicoradiographic analysis should obviate such errors and facilitate the correct diagnosis in the future.Ocul Oncol Pathol 2018;4:82-89
Source: Ocular Oncology and Pathology - Category: Opthalmology Source Type: research
ConclusionsWe confirmed the frequency-specific reorganization of the insula –DMN connectivity in FM. The clinical relevance of this connectivity change may warrant future studies to elucidate its causal relationship and potential as a neurological signature for FM.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
More News: Brain | MRI Scan | Neurology | Speech-Language Pathology | Study