Technique of proton and phosphorous MR spectroscopy.

[Technique of proton and phosphorous MR spectroscopy]. Radiologe. 2017 Mar 22;: Authors: Backens M Abstract CLINICAL/METHODICAL ISSUE: Magnetic resonance spectroscopy (MRS) is an important non-invasive method that can reveal the concentration and spatial distribution of particular biochemically relevant tissue metabolites. STANDARD RADIOLOGICAL METHODS: Proton MRS is routinely applicable in the clinical setting providing good quality results even with a moderate magnetic field strength of 1.5 T. Relative values of metabolite concentrations are mostly used for the assessment of metabolic disorders. METHODICAL INNOVATIONS: Absolute quantification of metabolites can be achieved by means of internal or external reference scans. Phosphorous MRS extends the range of detectable molecules to energy and cell membrane metabolism. PERFORMANCE: The lower detection limit of metabolite concentrations is in the range of some mmol/kg. Depending on the magnetic field strength, MRS enables a spatial resolution of a few milliliters. ACHIEVEMENTS: The use of phosphorous MRS is considerably limited because higher field strengths of at least 3.0 T and additional expensive hardware for signal processing are required. PMID: 28331946 [PubMed - as supplied by publisher]
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research

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