Importance of "epimmunome" as a new therapeutic target for allergic rhinitis.

IMPORTANCE OF "EPIMMUNOME" AS A NEW THERAPEUTIC TARGET FOR ALLERGIC RHINITIS. Arerugi. 2017;66(2):91-96 Authors: Kamekura R, Ichimiya S, Himi T PMID: 28331110 [PubMed - in process]
Source: Allergology International - Category: Allergy & Immunology Tags: Arerugi Source Type: research

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A consistent increase in the intensity and length of allergy season in regions of the United States signals a difficult season in 2020, at the same time as the COVID-19 pandemic affects communities.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news
‘Grandfather of allergy’ survived three years in Japanese POW camp before pioneering medical careerDr William Frankland, a pioneering British immunologist who transformed the world ’s understanding of allergies, has died aged 108.Frankland improved the lives of millions of hay fever sufferers by developing the idea of apollen count. Until his death the oldest survivor of the Japanese prisoner of war camps, he published a scientific paper in September 2017 aged 105.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Immunology Biochemistry and molecular biology Medical research Science UK news Hay fever Allergies Source Type: news
Condition:   Perennial Allergic Rhinitis Intervention:   Drug: Fluticasone Propionate Sponsor:   Libbs Farmacêutica LTDA Completed
Source: - Category: Research Source Type: clinical trials
In his long career, Dr. Frankland helped legions of hay fever sneezers by publicizing pollen counts. Among his many patients was Saddam Hussein.
Source: NYT Health - Category: Consumer Health News Authors: Tags: William Frankland Great Britain Deaths (Obituaries) Allergies Pollen Research Source Type: news
Authors: Degirmenci N, Dogan R, Tugrul S, Senturk E, Toprak A, Ozturan O Abstract OBJECTIVE: To evaluate the colour values of nasal mucosa for the purpose of presenting an objective parameter of allergic rhinitis. METHODS: Seventy-three patients with allergic rhinitis (allergy group) and 73 normal healthy individuals (control group) were included in the study. Endoscopic examinations were conducted, and endoscopic photographs of the septum and both inferior turbinates were taken. The Adobe Photoshop Elements 7.0 software program was used to measure the numerical values of red-green-blue (RGB) colour components ...
Source: Journal of Laryngology and Otology - Category: ENT & OMF Tags: J Laryngol Otol Source Type: research
Cell Death &Disease, Published online: 02 April 2020; doi:10.1038/s41419-020-2394-3The regulatory network among CircHIPK3, LncGAS5, and miR-495 promotes Th2 differentiation in allergic rhinitis
Source: Cell death and disease - Category: Internal Medicine Authors: Source Type: research
The number of metachromatic cells in nasal swabs in untreated subjects (B) and SCIT (C) for Japanese cedar pollinosis in pre ‐season and in season. AbstractBackground and objectiveNasal symptoms of allergic rhinitis can be reduced with allergen ‐specific subcutaneous immunotherapy (SCIT). However, the mechanisms underlying the effectiveness of SCIT for Japanese cedar pollinosis are not well understood. We studied changes in the numbers of metachromatic cells, eosinophils and neutrophils in nasal swabs following SCIT for Japanese cedar po llinosis.MethodsSubjects were either untreated or given SCIT for 0.5 to 13 years d...
Source: Immunity, Inflammation and Disease - Category: Allergy & Immunology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Conclusions: IDA significantly increases autoimmune disease risk, particularly in female patients and patients with certain comorbidities. Clinicians should conduct further clinical evaluations and laboratory tests of autoimmune disease in patients with IDA.Plain Language Summary: Little is known about the relationship between iron deficiency and autoimmune disease. By using a national-level database in Taiwan, we noted a meaningful association between iron deficiency anemia (IDA) and later autoimmune disease development. Our study extends the known disease range and recommends that physicians be alert for the occurrence o...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Mrs. S is an 85-year-old woman who moved into the nursing home five years ago when her husband could no longer provide care for her due to her progressive weakness and failure to thrive. She has a history of Barrett ’s esophagus and significant reflux and subsequent dysphagia, a long history of depression, allergic rhinitis, dementia with a Brief Interview for Mental Status (BIMS) score of 12, basal cell carcinoma, insomnia, iron deficiency anemia, and a pneumonitis due to aspiration. She is oxygen dependent.
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We present a case of a 51 ‐year‐old Japanese woman diagnosed with eosinophilic granulomatous polyangiitis (EGPA), a rare vasculitis that can occur in patients with eosinophilia and history of asthma, allergic rhinitis, and sinusitis, with immunoglobulin (Ig) G4 hypergammaglobulinaemia and salivary gland swelling. AbstractA 51 ‐year‐old woman was admitted to our hospital for cough, fever, purpura in the legs, and salivary gland swelling. Six years ago, she had been diagnosed with bronchial asthma and was treated with a combination of inhaled corticosteroid and long‐acting beta2‐agonist. Blood examination showed ...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
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