He Treated The Very First Ebola Cases 40 Years Ago. Then He Watched The World Forget.

This article is part of HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to fight them. KINSHASA, Congo ― In early 2014, few people worried that the Ebola virus, which is up to 90 percent fatal, would pose a global threat. So the World Health Organization sent shockwaves around the world when it announced that Ebola was spreading out of control in West Africa. Before the epidemic was over two years later, it had killed thousands of people. They died in terrifying and painful ways, often passing the disease on to family members before and even after death. Doctors and aid workers died, people who should have been able to stay safe while offering care. But not everyone who is exposed to the Ebola virus, which spreads through contact with blood or other bodily fluids, falls ill. Such is the case of Dr. Jean-Jacques Muyembe-Tamfum, who in 1976 became the first scientist to come into contact with Ebola and survive. The Congolese virologist, now 74, placed himself square in the path of the disease as he worked in harrowing and hazardous conditions to identify what was killing some of its earliest victims. “I am like Johnnie Walker,” he quipped, referencing the well-known Scotch whisky slogan, “Born 1820 ― Still going strong.” Muyembe giggled as he strode around his office imitating the brand’s iconic “Striding Man.” It’s a joke in service of a very seriou...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 15 June 2019Source: Nano TodayAuthor(s): Weijing Yang, Zijian Zhou, Joseph Lau, Shuo Hu, Xiaoyuan ChenAbstractImmunotherapy (e.g., checkpoint blockade, adoptive T cell therapy, cancer vaccine) has emerged as one of the most important treatment modalities for cancer in the past two decades. While these approaches are promising, the response rates observed in clinical trials are less than 30% due to tumor heterogeneity and complexity of the tumor microenvironment. Smart nanosystems have the potential to address some of the limitations associated with immunotherapy. Herein, we review applica...
Source: Nano Today - Category: Nanotechnology Source Type: research
Authors: Liu Y, Gao L, Lv W, Lın L, Wang Y, Fıang F, Feng F Abstract Background/aim: To prepare a porcine model of obstructive sleep apnea-hypopnea syndrome (OSAHS) and observe the pathological and hemodynamic changes in the common carotid artery. Materials and methods: Twelve male miniature pigs were randomly divided into the model and control group (n = 6). Pigs in the model group were kept in an air-flow negative pressure chamber at 0.96 ± 0.01 kPa, and the air oxygen content, temperature, and humidity were kept at normal culture conditions in both groups. After pigs in the model group presented sym...
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Publication date: Available online 15 June 2019Source: The Annals of Thoracic SurgeryAuthor(s): Magnus Dalén
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
CONCLUSION: Automated acoustic methods can help diagnose sleep-disordered breathing. A reason for the restricted recognition performance is the limited size of the training datasets. PMID: 31190193 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
CONCLUSION: The objective severity of OSA and the associated subjective daytime sleepiness was reduced in both groups. There was no difference in terms of clinical outcome or compliance between the gradual or intensive SPT therapy in POSA patients during the observation period. Both training modalities are highly successful and well tolerated. PMID: 31190192 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Abstract Background: Chronic migraine with medication overuse headache (CM-MOH) is the most common type of chronic migraine, and it increases risk of stroke and white matter lesions. These pathologic changes could induce cognitive decline. However, the alteration of cognitive function in CM-MOH patients is not established. Therefore, we took this study to reveal the cognitive performances in CM-MOH. Methods: This cross-sectional study was conducted between December 2015 and January 2017. Patients were divided into CM-MOH, CMwoMOH (chronic migraine without medication overuse), and MO (migraine without aura) gr...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Abstract Although the life-course concept of risk markers as potential etiological influences is well established in epidemiology, it has not featured in academic publications or clinical practice in the context of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS). Studies of risk markers are required considerations for evaluation of patients and for research because there is no single cause, pathological feature, laboratory finding, or biomarker for CWP or FMS. The early-life risk markers identified by extensive literature review with best evidence for potential causal influence on the development and...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Conclusion: Our study revealed a strong association between a variant in COL8A1 (rs13095226) and exudative AMD development. PMID: 31191752 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
New UK research predicts extremes of weather will hit food productionGlobal heating could bring many more bouts of severe drought as well as increased flooding to Africa than previously forecast, scientists have warned.New research says the continent will experience many extreme outbreaks of intense rainfall over the next 80 years. These could trigger devastating floods, storms and disruption of farming. In addition, these events are likely to be interspersed with more crippling droughts during the growing season and these could also damage crop and food production.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Climate change Flooding Natural disasters and extreme weather Drought Environment Science Africa World news Source Type: news
Conclusion: The ToT model was successful, nurses initiated CPAP most commonly, prematurity with acute respiratory distress syndrome was the most common indication, and adverse events were uncommon. PMID: 31190634 [PubMed - as supplied by publisher]
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
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