Evolutionary gain of highly divergent tRNA specificities by two isoforms of human histidyl-tRNA synthetase.

This study suggests that the human HisRS genes, while descending from a common ancestor with dual function for both types of tRNA(His), have acquired highly specialized tRNA recognition properties through evolution.
PMID: 28321488 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Life Sciences : CMLS - March 20, 2017 Category: Cytology Authors: Lee YH, Chang CP, Cheng YJ, Kuo YY, Lin YS, Wang CC Tags: Cell Mol Life Sci Source Type: research