Stress may protect -- at least in bacteria

(Institute of Science and Technology Austria) Antibiotics harm bacteria and stress them. Trimethoprim, an antibiotic, inhibits the growth of the bacterium Escherichia coli and induces a stress response. This response also protects the bacterium from subsequent deadly damage from acid. Antibiotics can therefore increase the survival chances of bacteria under certain conditions. This is shown in a study by researchers at IST Austria (Karin Mitosch, Georg Rieckh and Tobias Bollenbach), which was published in the journal Cell Systems.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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(American Institute of Physics) Biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions. To be successful, they must consist of materials that can pass through the body's immune response, swim quickly through viscous environments and penetrate tissue cells to deliver cargo. In APL Bioengineering, researchers fabricated biohybrid bacterial microswimmers by combining a genetically engineered E. coli MG1655 substrain and nanoerythrosomes, small structures made from red blood cells.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Publication date: Available online 6 April 2020Source: Food ControlAuthor(s): Johanne Ellis-Iversen, Mette R. Gantzhorn, Birgitte Borck Høg, Alessandro Foddai, Maarten Nauta
Source: Food Control - Category: Food Science Source Type: research
Conclusions: Great care should be taken as to whether the underlying network model correctly captures the spreading mechanism of the outbreak in terms of spatial scale and single or multiple source outbreak.
Source: Epidemiology - Category: Epidemiology Tags: Environmental Epidemiology Source Type: research
Roberto Pilloton Norovirus is one of the leading causes of gastroenteritis, acute vomiting, intense diarrhoea, acute pain in the stomach, high fever, headaches, and body pain. Conventional methods of detection gave us very promising results but had disadvantages such as low sensitivity, cost ineffectiveness, reduced specificity and selectivity, etc. Therefore, biosensors can be a viable alternative device which can overcome all setbacks associated with the conventional method. An electrochemical sensor based on oxidized graphitic carbon nitride (Ox-g-C3N4) modified electrochemical paper-based analytical device (ePAD) ...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
The objective of this study was to apply an in vitro bioguided approach using as a model system the mollicutes with a sample of propolis from the Brazilian native bee Melipona quadrifasciata (mandaçaia) in order to identify potential new molecules with antimicrobial activity. A crude hydroalcoholic extract was obtained and submitted to liquid-liquid partitioning with solvents of different polarities, generating four different fractions: aqueous, dichloromethane, butanol, and ethyl acetate fractions. The antimollicute activity assays served as a basis for the bioguided fractionation. The dichloromethane fraction was ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
asia N. Vlasova Rotaviruses (RVs) are the leading cause of the acute viral gastroenteritis in young children and livestock animals worldwide. Although live attenuated vaccines have been applied to control RV infection for many years, the underlying mechanisms of RV attenuation following cell culture adaption are unknown. To study these mechanisms at the genomic level, we have sequenced and conducted a comparative analysis of two virulent human (Wa, G1P[8] and M, G3P[8]) and two virulent porcine (Gottfried, G4P[6] and OSU, G5P[7]) RV strains maintained in gnotobiotic piglets for 22, 11, 12 and 9 serial passages, respect...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
This study represents the first characterization of a mobilizable antibiotic resistance island in a species of Rheinheimera and provides evidence that Rheinheimera spp. could be important reservoirs and vehicles for ARGs in the Yellow Sea area.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
cala Gulino Fragalà Zinc oxide (ZnO) nanorods grown by chemical bath deposition (CBD) on the surface of polyetheresulfone (PES) electrospun fibers confer antimicrobial properties to the obtained hybrid inorganic–polymeric PES/ZnO mats. In particular, a decrement of bacteria colony forming units (CFU) is observed for both negative (Escherichia coli) and positive (Staphylococcus aureus and Staphylococcus epidermidis) Grams. Since antimicrobial action is strictly related to the quantity of ZnO present on surface, a CBD process optimization is performed to achieve the best results in terms of coverag...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionThe incidence of post-transplant UTI is similar in both developed and developing countries.E.coli is the most common pathogen in most of studies. Cadaveric donor and post-dialysis transplantation are defined as independent risk factors for post-transplant UTI. Further studies are still required to identify risk factors after kidney transplantation and UTI ’s importance for graft function and patient outcome.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 5 April 2020Source: Materials Chemistry and PhysicsAuthor(s): Nhamo Chaukura, Gerald Katengeza, Willis Gwenzi, Chiedza I. Mbiriri, Thabo TI. Nkambule, Mambo Moyo, Alex T. Kuvarega
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
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