Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation and systemic markers.

CONCLUSIONS: Elevated aromatase in the setting of adipose dysfunction provides a possible mechanism for the higher incidence of hormone-dependent breast cancer in obese women after menopause.
PMID: 28323914 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - February 16, 2017 Category: Endocrinology Authors: Brown KA, Iyengar NM, Zhou XK, Gucalp A, Subbaramaiah K, Wang H, Giri DD, Morrow M, Falcone DJ, Wendel NK, Winston LA, Pollak M, Dierickx A, Hudis CA, Dannenberg AJ Tags: J Clin Endocrinol Metab Source Type: research