Inflammation: Hit the DEK!

Nature Reviews Rheumatology 13, 196 (2017).
doi:10.1038/nrrheum.2017.25

Author: Sarah Onuora
An aptamer targeting the nuclear chromatin protein DEK blocks neutrophil extracellular trap (NET) formation and the development of arthritis in a mouse model, according to new research published in Nature Communications. “As DEK has been implicated in the pathogenesis of juvenile idiopathic arthritis (JIA)

Source: Nature Reviews Rheumatology - February 23, 2017 Category: Rheumatology Authors: Sarah Onuora Tags: Research Highlight Source Type: research