Electrospun protein nanofibers in healthcare: A review

Publication date: 15 May 2017 Source:International Journal of Pharmaceutics, Volume 523, Issue 1 Author(s): S. Babitha, Lakra Rachita, K. Karthikeyan, Ekambaram Shoba, Indrakumar Janani, Balan Poornima, K. Purna Sai Electrospun nanofibers are being utilized for a wide range of healthcare applications. A plethora of natural and synthetic polymers are exploited for their ability to be electrospun and replace the complex habitat provided by the extracellular matrix for the cells. The fabrication of nanofibers can be tuned to act as a multicarrier system to deliver drugs, growth factors and health supplements etc. in a sustained manner. Owing to its pliability, nanofibers reached its heights in tissue engineering and drug delivery applications. This review mainly focuses on various standardized parameters and optimized blending ratios for animal and plant proteins to yield fine, continuous nanofibers for effective utilization in various healthcare applications. Graphical abstract
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research