Clinical trials designed to block autophagy in multiple cancers show promise

(University of Pennsylvania School of Medicine) In the largest group of results to date, researchers from Penn Medicine's Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine blocked autophagy in a host of aggressive cancers -- glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers -- and in some cases helped stabilize disease.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news