Dietary Alterations Caused by microRNA: Can food be medicinal?

Dietary Alterations Caused by microRNA: Can food be medicinal?
Ageing Res Rev. 2014 May 12;
Authors: Palmer JD, Soule BP, Simone BA, Zaorsky NG, Jin L, Simone NL
Abstract
As the link between metabolism and major disease processes becomes more well-defined, the identification of key molecular targets is leading to new therapeutic strategies. As a result, small non-coding RNA molecules that regulate gene expression via epigenetic alterations, microRNAs have been identified as regulators of these metabolic processes. In the last decade, dietary interventions have been used to change metabolism and to potentially alter disease progression and clinical outcomes. These interventions have been linked, at a molecular level, to microRNAs. This review will summarize the role of various dietary strategies on the expression of several microRNA families.
PMID: 24833329 [PubMed - as supplied by publisher]

Source: Ageing Research Reviews - May 12, 2014 Category: Genetics & Stem Cells Authors: Palmer JD, Soule BP, Simone BA, Zaorsky NG, Jin L, Simone NL Tags: Ageing Res Rev Source Type: research