Thyroid V40 Predicts Primary Hypothyroidism Following Intensity Modulated Radiotherapy for Nasopharyngeal Carcinoma
Primary hypothyroidism (HT) is a common occurrence after intensity modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC). This is a study to investigate the various clinical and thyroid dosimetric parameters that could predict the risk of primary hypothyroidism after IMRT and to determine useful thyroid dose constraints to guide radiotherapy planning. Thyroid V40 is predictive of primary hypothyroidism following intensity modulated radiotherapy for nasopharyngeal carcinoma and V40 ≤85% can be a useful dose constraint to adopt during IMRT planning without compromising tumor coverage.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Kiattisa Sommat, Whee Sze Ong, Ashik Hussain, Yoke Lim Soong, Terence Tan, Joseph Wee, Kam Weng Fong Tags: Clinical Investigation Source Type: research
More News: Biology | Cancer & Oncology | Carcinoma | Hypothyroidism | Intensity-Modulated Radiation Therapy | Nasopharyngeal Cancer | Physics | Radiology | Study | Thyroid | Thyroid Cancer