The Use of Zonisamide for the Treatment of Psychiatric Disorders: A Systematic Review

Conclusions: Zonisamide may have some utility, especially as an adjunctive therapy, for the management of acute phases and weight gain in bipolar disorder and for prevention of alcohol misuse. Preliminary evidence indicates zonisamide as a candidate compound for the treatment of BED and obesity. However, open-label design and small sample sizes of most available studies prevent from drawing sound conclusions about the utility of this compound in psychiatry.
Source: Clinical Neuropharmacology - Category: Neurology Tags: Review Articles Source Type: research

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Little is known regarding the association between alcohol use and violence among community college women. Accordingly, this study investigated daily-level associations between alcohol use and intimate partner victimization (IPV) in a sample of young women ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Authors: Leite DFB, Cecatti JG Abstract The actual burden and future burden of the small-for-gestational-age (SGA) babies turn their screening in pregnancy a question of major concern for clinicians and policymakers. Half of stillbirths are due to growth restriction in utero, and possibly, a quarter of livebirths of low- and middle-income countries are SGA. Growing body of evidence shows their higher risk of adverse outcomes at any period of life, including increased rates of neurologic delay, noncommunicable chronic diseases (central obesity and metabolic syndrome), and mortality. Although there is no consensus re...
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
CONCLUSIONS: Caregivers are engaging in a range of health risk behaviours; however, rates of hazardous alcohol consumption among the sample were high. Health promotion interventions targeted to address alcohol consumption should consider caregiver age and country of residence. So what? This study highlights the health risk behaviours caregivers engage in across a number of countries, and suggests that caregivers require further support to manage alcohol consumption in particular. PMID: 31529552 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
hey all, I’m doing a significant amount genicular RFA with mixed results. Mainly in patients who are non-surgical candidate with severe knee osteoarthritis, morbid obesity etc. I work in the hospital when I started they already had coolief so I have been using that exclusively. Used it in fellowship. based on the Franco cadaver study, the superior medial and superior lateral Lie in the 50th to 75th percent depth of the distal femur, So I do two lesions at the sites (even with cooled), one... Genicular RFA. Any input helpful!
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
DISCUSSION: Using a new and freely-available Canadian walkability index, this study observed a positive association between walkability and both measured obesity and self-rated general health in adults. Walkability is one of many built environment characteristics that should be considered when trying to understand the relative contribution of the built environment to a person's weight and overall health. PMID: 31532539 [PubMed - in process]
Source: Health Reports - Category: International Medicine & Public Health Tags: Health Rep Source Type: research
An artificial intelligence (AI) algorithm was able to automatically quantify...Read more on AuntMinnie.comRelated Reading: Ultrasound useful for evaluating liver steatosis MRI offers view of liver fat loss in obese patients Ultrasound options abound for diagnosing liver disease AIUM: Can deep learning classify liver fibrosis on US? Fatty liver disease occurs with risky plaque
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Find out how the combination of conjugated estrogens and bazedoxifene impacts beta-cell function to improve obesity and in return, reduce the risk for type 2 diabetes.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Authors: Grijalva-Avila J, Villanueva-Fierro I, Lares-Asseff I, Chairez-Hernández I, Rivera-Sanchez G, Martínez-Estrada S, Martínez-Rivera I, Quiñones LA, Loera-Castañeda V Abstract Mexico ranks 2nd in adult obesity and 4th in milk intake worldwide. Low levels of IGF-1 have been related to obesity and can be reverted by milk intake. The rs6214 polymorphism has been associated with an increase in the expression of IGF-1. Therefore, the aim of the study was to evaluate the association between both, rs6214 polymorphism and milk intake, and obesity. We analysed 99 adult volunteers, wi...
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Publication date: Available online 14 September 2019Source: International Journal of PharmaceuticsAuthor(s): Alice Melocchi, Marco Uboldi, Nicoletta Inverardi, Francesco Briatico-Vangosa, Francesco Baldi, Stefano Pandini, Giulia Scalet, Ferdinando Auricchio, Matteo Cerea, Anastasia Foppoli, Alessandra Maroni, Lucia Zema, Andrea GazzanigaAbstractSeveral diseases would benefit from prolonged drug release provided by systems retained in the stomach for extended time periods. Expandable gastroretentive devices are administered in a collapsed configuration enabling swallowing and regain in situ their native shape having larger ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs
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