Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity

Conclusions
Compared with patients with DM or PM, IMNM is characterised by more widespread muscle involvement. Anti-SRP-positive patients have more severe muscle involvement than anti-HMGCR-positive patients.

Source: Annals of the Rheumatic Diseases - March 9, 2017 Category: Rheumatology Authors: Pinal-Fernandez, I., Casal-Dominguez, M., Carrino, J. A., Lahouti, A. H., Basharat, P., Albayda, J., Paik, J. J., Ahlawat, S., Danoff, S. K., Lloyd, T. E., Mammen, A. L., Christopher-Stine, L. Tags: Immunology (including allergy), Muscle disease, Connective tissue disease, Musculoskeletal syndromes Clinical and epidemiological research Source Type: research