Request for Applications: Clinical and Translational Pediatric Lupus Nephritis Biomarker Panel Research

Request for Applications: Clinical and Translational Pediatric Lupus Nephritis Biomarker Panel Research Award Amount: $500,000 ($100,000 per year for five years) Letter of Intent Deadline: May 30, 2014 at 5 p.m. EST Application Deadline: June 30, 2014 at 5 p.m. EST Earliest Award Date: September 5, 2014 On behalf of the Michael Jon Barlin Pediatric Research Program, the Lupus Foundation of America issues this request for application (RFA) to address a critical need in pediatric lupus nephritis. Lupus nephritis is one of the most severe and pervasive organ manifestations of lupus, affecting up to 80% of children and adolescents with lupus. Up to 40% of children with lupus nephritis may progress to end-stage renal disease—permanent failure of the kidneys. Thus, lupus nephritis warrants close medical monitoring. Traditional measures used to monitor lupus nephritis are unable to determine disease activity and progression or predict flares while the patient is in the doctor’s office. Thus, clinical decisions may have to be made after the doctor’s visit, which is suboptimal. The development of a real-time test (or assay), which would allow for more targeted treatment decisions and more personalized care, could change the future for many children living with lupus nephritis. For these reasons, and many more, there is a dire unmet need to develop and test a lupus nephritis biomarker panel that has the potential to monitor, stratify, and p...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding