Is central sensitisation really a thing?

It seems odd to me that there’s much argument about central sensitisation in pain circles. I thought the idea of central sensitisation was well-established based on research from some years ago – but apparently there are still arguments about its relevance, and lots of debate about how to identify it clinically. This post is based mainly on a presentation by Jo Nijs from Pain in Motion, at the recent NZ Pain Society meeting in Nelson. In this post I want to briefly review the material presented by Jo suggesting that central sensitisation is a thing. I’ll write more about assessment in a future blog, or this post will be the longest ever! Firstly, what is it and why should it matter? Researchers have long been aware that when a nerve is repeatedly stimulated, in future stimulation it will respond for longer and with more intensity – this is called long-term potentiation. Recently, the contribution of glial cells to this situation has been identified (remember glia? Those little cells whose purpose no-one really knew? Turns out they release gliotransmitters that circulate throughout the spinal cord and allow information to be transmitted widely, far from the original source of stimulation – see Kronschlager, Drdla-Schutting, Gassner, Honsek et al, (2016). Glial cells occur widely throughout the central nervous system, and while LTP is a process we’ve known about in the CNS for some time – we’ve known because this is how “mem...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: Chronic pain Clinical reasoning Pain conditions Research Science in practice biopsychosocial Health Source Type: blogs

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Source: Journal of Cardiopulmonary Rehabilitation - Category: Rehabilitation Tags: Systematic Review Source Type: research
Hi everyone. Long time lurker here. I'm aware I can search the forums and I have but some of the information is somewhat dated, in particular software. I am planning to open a new pain practice and would appreciate some advice if any of you who own or run a pain practice can provide some answers What EMR system are you using and what are they charging? Kareo, Athena? Others? Does it do it all? Scheduling, charting, billing? What do you like about it or not like about it? What do you use... new practice questions
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
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Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: CME: Rheumatology Source Type: research
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Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: Case Report Source Type: research
UCLA has received a $10 million gift fromThe Eli and Edythe Broad Foundation to fund education, faculty recruitment and retention, and innovative research at the campus ’s stem cell research center. The foundation also announced $10 million gifts to the Broad family’s namesake stem cell research centers UC San Francisco and the University of Southern California, bringing its total support of stem cell research centers in California to $110 million since 2005.      “We are proud to support California’s growing stem cell research and treatment infrastructure led by the talented sci...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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