What is the Ideal Route of Administration of Tranexamic Acid in TKA? A Randomized Controlled Trial.

CONCLUSION: IA tranexamic acid administration further reduces blood loss after TKA in comparison to IV use alone; no additional effect in further reducing blood loss was found in combination with IV tranexamic acid. Appropriately powered studies are needed to confirm the safety of this route of administration as the preferred route of administration in TKA. LEVEL OF EVIDENCE: Level I, therapeutic study. PMID: 28283902 [PubMed - as supplied by publisher]
Source: Clinical Orthopaedics and Related Research - Category: Orthopaedics Authors: Tags: Clin Orthop Relat Res Source Type: research