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Hormone replacement therapy reduces risk of early death

Women who use hormone replacement therapy have significantly decreased risk of heart attack or stroke, according to a study being presented at the American College of Cardiology’s 66th Annual Scientific Session& Expo on 17 March.Telegraph
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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The objective of the study was to compare the vasodilator efficacy of topical 10% nifedipine versus 5% sildenafil in subjects with secondary RP associated with connective tissue disease. A prospective study was performed including 10 patients with secondary RP. We excluded tobacco smokers, patients with primary RP, hypotension, hypertension, myocardial infarction, stroke, or arrhythmia.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Tags: Research letter Source Type: research
Conclusions The present study points to the feasibility and safety of performing PCI in multivessel diabetic patients, especially among those with low angiographic complexity. Incomplete revascularization was a predictor of a higher occurrence of MACCE in the medium/long‐term follow‐up.
Source: Revista Brasileira de Cardiologia Invasiva - Category: Cardiology Source Type: research
[03-03-2015] The U.S. Food and Drug Administration (FDA) cautions that prescription testosterone products are approved only for men who have low testosterone levels caused by certain medical conditions.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Source Type: news
SNOWY weather over the weekend has been followed by cold snap that could trigger an increase in the number of heart attacks and strokes, the NHS has warned.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ABSTRACT Background: Blood biomarkers are easily accessible and might reflect chronic obstructive pulmonary disease (COPD) activity. Aim: To determine whether a panel of blood biomarkers (C‐reactive protein [CRP], neutrophils, eosinophils, albumin and vitamin D) could predict mortality in COPD. Methods: we analyzed data from 431 COPD participants to the 2007‐2010 National Health and Nutrition Examination Surveys who were followed for a median time of 36 months. COPD was defined as post‐bronchodilator forced expiratory volume in 1 second (FEV1) and forced vital capacity ratio
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
AbstractSystemic lupus erythematosus (SLE) is a significant risk factor for cardiovascular disease. The relationship between SLE and perioperative cardiovascular risks following non-cardiac surgery is uncertain. We investigated associations between a diagnosis of SLE and outcomes following major non-cardiac surgery in a large national database from the United States. Patients age  ≥ 18 years requiring major non-cardiac surgery were identified from Healthcare Cost and Utilization Project’s National Inpatient Sample data from 2004 to 2014. Systemic lupus erythematosus and perioperative major adver...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Authors: Chaturvedi S, Hachinski V Abstract Preview All transient ischemic attacks are not created equal. However, they are a medical emergency, and all patients should be hospitalized for urgent evaluation of their risk for stroke or myocardial infarction. For optimal management, it must be determined whether an ischemic attack affects the anterior or posterior circulation. In this article, the authors review current medical options for stroke prevention and the indications for carotid endarterectomy. PMID: 29219705 [PubMed]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
CONCLUSIONS: In a community-based sample of Japanese men free of CHD and stroke, CAC score ≥100 was significantly associated with higher estimated CHD risk by prediction models. This finding supports the potential utility of CAC as a biomarker for CHD in a general Japanese male population. PMID: 29212987 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
AbstractBackgroundIn patients already receiving combination of angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) and calcium channel blocker (CCB), whether the choice of additional diuretic or beta-blocker affects the cardiovascular and cerebrovascular outcomes remains unclear.MethodsA total of 13,551 patients who were concurrently receiving three anti-hypertensive agents of different classes through outpatient clinics during 2004 −2006 were identified from the National Health Insurance Research Database of Taiwan. Patients were further classified into two treatment groups according to...
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
AbstractBackgroundNo direct comparisons of ticagrelor and prasugrel with 1-year clinical follow-up have been reported.ObjectivesOur objective was to compare 1-year clinical outcomes among patients with acute coronary syndrome (ACS) managed with percutaneous coronary intervention (PCI) and treated with either ticagrelor or prasugrel in a real-world setting.MethodsThis retrospective study included patients from a payer database who were aged ≥18 years and had ACS managed with PCI with no history of transient ischemic attack (TIA)/stroke. Data were propensity matched for prasugrel use with a 3:1 prasugrel:ticagrelor r...
Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
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