RNA and longevity: Discovering the mechanisms behind aging

(Pohang University of Science& Technology (POSTECH)) Korean researchers suggests that NMD-mediated RNA quality control is critical for longevity in the roundworm called C. elegans, a popularly used animal for aging research. They first discovered that NMD activity decreases during aging. The team then discovered that enhanced NMD underlies the longevity of famous C. elegans strains called daf-2 mutants, which have reduced insulin hormone signaling. This achievement has been published in the world-renowned Nature Communications.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news