The Hot and Potential Targets of Type 2 Diabetes Mellitus Treatment in Recent Decade.

This article is intended to provide a broad ranging overview of 14 prominent molecule targets currently being pursued for the treatment of diabetes, with regard to their therapeutic rationale, small molecule modulators and application prospects. These targets are roughly divided into four general areas that correlate with insulin secretion, act on the insulin sensitivity, and have an effect on the complications. This article could provides the medicinal chemist interested in discovering novel therapeutic small molecules with a myriad of promising diabetes targets and broader development space for treating T2DM. PMID: 28270085 [PubMed - as supplied by publisher]
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research