Adipokines as atherothrombotic risk factors in obese subjects: associations with haemostatic markers and common carotid wall thickness

Some crucial associations between obesity-related altered adipokine levels and the main factors of atherosclerotic, atherothrombotic processes are not fully known. We analysed the relationships of classic adipokines, namely leptin, resistin, adiponectin, tumor necrosis factor-alpha (TNF- α), interleukin 6 (IL-6) with the markers of platelet activation, including mean platelet volume (MPV), platelet surface/soluble P-selectin, platelet-derived microparticles (PMPs), the parameters of coagulation abnormalities and common carotid intima-media thickness (IMT) in obese patients with or without atherosclerotic comorbidities in comparison to age- and sex-matched controls.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 7, 2017 Category: Nutrition Authors: Éva Csongrádi, Miklós Káplár, Béla Nagy Jr, Christian A. Koch, Attila Juhász, László Bajnok, Zsuzsa Varga, Ildikó Seres, Zsolt Karányi, Mária T. Magyar, László Oláh, Andrea Facskó, János Kappelmayer, György Paragh Source Type: research